Genotype–phenotype links in frontotemporal lobar degeneration
S Van Mossevelde, S Engelborghs… - Nature Reviews …, 2018 - nature.com
Frontotemporal lobar degeneration (FTLD) represents a group of neurodegenerative brain
diseases with highly heterogeneous clinical, neuropathological and genetic characteristics …
diseases with highly heterogeneous clinical, neuropathological and genetic characteristics …
Genetics of frontotemporal lobar degeneration: an up-date and diagnosis algorithm
I Le Ber - Revue neurologique, 2013 - Elsevier
The last decade marked a turning point in the knowledge of frontotemporal lobar
degenerations (FTLD). Major discoveries were made with the identification of TDP-43 and …
degenerations (FTLD). Major discoveries were made with the identification of TDP-43 and …
Update on recent molecular and genetic advances in frontotemporal lobar degeneration
EH Bigio - Journal of Neuropathology & Experimental …, 2008 - academic.oup.com
Great strides have been made in the last 2 years in the field of frontotemporal lobar
degeneration (FTLD), particularly with respect to the genetics and molecular biology of FTLD …
degeneration (FTLD), particularly with respect to the genetics and molecular biology of FTLD …
The genetics and neuropathology of frontotemporal lobar degeneration
A Sieben, T Van Langenhove, S Engelborghs… - Acta …, 2012 - Springer
Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders
characterized by disturbances of behavior and personality and different types of language …
characterized by disturbances of behavior and personality and different types of language …
A new algorithm for molecular diagnostics in FTLD
B Borroni, A Padovani - Nature Reviews Neurology, 2013 - nature.com
Genetic diagnosis of frontotemporal lobar degeneration has become challenging since the
identification of a number of autosomal dominantly inherited causative mutations. As …
identification of a number of autosomal dominantly inherited causative mutations. As …
Frontotemporal lobar degeneration
KA Josephs - Neurologic clinics, 2007 - Elsevier
Frontotemporal lobar degeneration (FTLD) is a syndromic diagnosis that encompasses at
least three different variants. Imaging modalities are clinically useful in FTLD, although …
least three different variants. Imaging modalities are clinically useful in FTLD, although …
Molecular pathology of frontotemporal lobar degenerations
Frontotemporal lobar degeneration (FTLD) is a group of disorders that principally affect the
frontal and temporal lobes of the brain. In many parts of the world, FTLD is rapidly becoming …
frontal and temporal lobes of the brain. In many parts of the world, FTLD is rapidly becoming …
The genetics of frontotemporal lobar degeneration
R Rademakers, M Hutton - Current neurology and neuroscience reports, 2007 - Springer
The clinical disorders associated with frontotemporal lobar degeneration (FTLD) are
increasingly recognized as an important cause of early-onset dementia. Patients usually …
increasingly recognized as an important cause of early-onset dementia. Patients usually …
Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease
Frontotemporal lobar degeneration with TAR DNA-binding protein 43 inclusions (FTLD-
TDP) is the most common pathology associated with frontotemporal dementia (FTD). Repeat …
TDP) is the most common pathology associated with frontotemporal dementia (FTD). Repeat …
Frontotemporal lobar degeneration—building on breakthroughs
J Van Der Zee, C Van Broeckhoven - Nature Reviews Neurology, 2014 - nature.com
Genetic research in frontotemporal lobar degeneration (FTLD) is gaining momentum.
Following the discovery of a repeat expansion in the gene C9 open reading frame 72 …
Following the discovery of a repeat expansion in the gene C9 open reading frame 72 …