Microglia and non-parenchymal macrophages in the brain are mononuclear phagocytes that
are increasingly recognized to be essential players in the development, homeostasis and …

For decades, microglia, the resident macrophages of the brain, have been recognized
mostly for their role in several, if not all, pathologies affecting the brain. However, several …

Microglia are parenchymal macrophages of the CNS; as professional phagocytes they are
important for maintenance of the brain's physiology. These cells are generated through …

Mononuclear phagocytic cells in the CNS used to be defined according to their anatomical
location and surface marker expression. Recently, this concept has been challenged by the …

Microglia are the resident macrophages of the central nervous system (CNS), which sit in
close proximity to neural structures and are intimately involved in brain homeostasis. The …

Microglia are highly specialized tissue macrophages of the brain with dedicated functions in
neuronal development, homeostasis and recovery from pathology Despite their unique …

It has recently emerged that microglia, the tissue-resident macrophages of the central
nervous system, play significant non-innate immune roles to support the development …

Microglia are brain macrophages that emerge from early erythro-myeloid precursors in the
embryonic yolk sac and migrate to the brain mesenchyme before the blood brain barrier is …

Brain macrophages include microglia in the parenchyma, border-associated macrophages
in the meningeal-choroid plexus-perivascular space, and monocyte-derived macrophages …

An explosion of findings driven by powerful new technologies has expanded our
understanding of microglia, the resident immune cells of the central nervous system (CNS) …