Peptide-based imaging agents for cancer detection

X Sun, Y Li, T Liu, Z Li, X Zhang, X Chen - Advanced drug delivery reviews, 2017 - Elsevier
Selective receptor-targeting peptide based agents have attracted considerable attention in
molecular imaging of tumor cells that overexpress corresponding peptide receptors due to …

Peptides as carrier for tumor diagnosis and treatment

M Langer, AG Beck-Sickinger - Current Medicinal Chemistry …, 2001 - ingentaconnect.com
The specific binding of peptides to their receptors can be used to meet the key requirement
in tumor targeting: selective addressing of neoplasm. Because of their small size, peptides …

Peptide-based probes for targeted molecular imaging

S Lee, J Xie, X Chen - Biochemistry, 2010 - ACS Publications
Targeted molecular imaging techniques have become indispensable tools in modern
diagnostics because they provide accurate and specific diagnosis of disease information …

[HTML][HTML] Seek & Destroy, use of targeting peptides for cancer detection and drug delivery

V Le Joncour, P Laakkonen - Bioorganic & medicinal chemistry, 2018 - Elsevier
Accounting for 16 million new cases and 9 million deaths annually, cancer leaves a great
number of patients helpless. It is a complex disease and still a major challenge for the …

Tumor-targeting peptides: ligands for molecular imaging and therapy

N Zhao, Y Qin, H Liu, Z Cheng - Anti-Cancer Agents in …, 2018 - ingentaconnect.com
The aberrant proliferation of tumor cells and abundant vasculature in tumor tissues are
closely correlated with receptors that are specifically dysregulated in tumor cells. These …

Multimodal tumor-targeting peptides functionalized with both a radio-and a fluorescent label

J Kuil, AH Velders, FWB van Leeuwen - Bioconjugate chemistry, 2010 - ACS Publications
The use of monolabeled tumor-targeting peptides for molecular imaging is widespread.
However, it is often desirable to use the same compound for different clinical applications …

Synthesis of target-specific radiolabeled peptides for diagnostic imaging

J Fichna, A Janecka - Bioconjugate chemistry, 2003 - ACS Publications
Radiopharmaceuticals are drugs containing atoms of some radioactive elements. They are
designed for diagnostic or therapeutic purposes, to deliver small doses of ionizing radiation …

Peptide‐based radiopharmaceuticals: Future tools for diagnostic imaging of cancers and other diseases

SM Okarvi - Medicinal research reviews, 2004 - Wiley Online Library
An Erratum has been published for this article in Medicinal Research Reviews 2004; 24: 685–
686. Small synthetic receptor‐binding peptides are the agents of choice for diagnostic …

Molecular imaging targeting peptide receptors

M Schottelius, HJ Wester - Methods, 2009 - Elsevier
Overexpressed neuropeptide receptors allow tumor visualization using eg radiolabeled
peptidic receptor ligands and positron emission tomography (PET) or single photon …

Influence of labelling methods on biodistribution and imaging properties of radiolabelled peptides for visualisation of molecular therapeutic targets

V Tolmachev, A Orlova - Current medicinal chemistry, 2010 - ingentaconnect.com
Progress in genomics and proteomics provides clinical oncology with new anti-cancer
drugs, which target selectively aberrantly expressed membrane proteins and associated …