Biomarkers of chondrocyte apoptosis and autophagy in osteoarthritis
G Musumeci, P Castrogiovanni, FM Trovato… - International journal of …, 2015 - mdpi.com
Cell death with morphological and molecular features of apoptosis has been detected in
osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte death/survival in the …
osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte death/survival in the …
Insights on molecular mechanisms of chondrocytes death in osteoarthritis
E Charlier, B Relic, C Deroyer, O Malaise… - International journal of …, 2016 - mdpi.com
Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …
Chondrocyte apoptosis in the pathogenesis of osteoarthritis
HS Hwang, HA Kim - International journal of molecular sciences, 2015 - mdpi.com
Apoptosis is a highly-regulated, active process of cell death involved in development,
homeostasis and aging. Dysregulation of apoptosis leads to pathological states, such as …
homeostasis and aging. Dysregulation of apoptosis leads to pathological states, such as …
Research progress on osteoarthritis treatment mechanisms
YT Gu, J Chen, ZL Meng, WY Ge, YY Bian… - Biomedicine & …, 2017 - Elsevier
Osteoarthritis is a common disease and is frequently encountered in the older population;
the incidence rises sharply with age. It is estimated that more than 360 million people suffer …
the incidence rises sharply with age. It is estimated that more than 360 million people suffer …
Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model
M Almonte-Becerril, F Navarro-Garcia… - Apoptosis, 2010 - Springer
The death of chondrocytes and the loss of extracellular matrix are the central features in
cartilage degeneration during Osteoarthritis (OA) pathogenesis. The mechanism by which …
cartilage degeneration during Osteoarthritis (OA) pathogenesis. The mechanism by which …
The role of apoptosis in the pathogenesis of osteoarthritis
SQ Xiao, M Cheng, L Wang, J Cao, L Fang… - International …, 2023 - Springer
Purpose Apoptosis is an important physiological process, making a great difference to
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …
development and tissue homeostasis. Osteoarthritis (OA) is a chronic joint disease …
Cell death and apoptosis in ostearthritic cartilage
HA Kim, FJ Blanco - Current drug targets, 2007 - ingentaconnect.com
Osteoarthritis (OA) is the most common chronic joint disease in the elderly population,
causing significant pain and disability. Because the cardinal feature of OA is a progressive …
causing significant pain and disability. Because the cardinal feature of OA is a progressive …
The dual role of autophagy in chondrocyte responses in the pathogenesis of articular cartilage degeneration in osteoarthritis
J Chang, W Wang, H Zhang, Y Hu… - International …, 2013 - spandidos-publications.com
The present study aimed to analyze the responses to autophagy in osteoarthritis (OA) and
aging chondrocytes in order to elucidate the role of autophagy in the pathogenesis of OA …
aging chondrocytes in order to elucidate the role of autophagy in the pathogenesis of OA …
Chondrocyte apoptosis: a cause or consequence of osteoarthritis?
Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage
degradation and changes in the subchondral bone. Over the last two decades, there has …
degradation and changes in the subchondral bone. Over the last two decades, there has …
Osteoarthritis chondrocytes die by apoptosis: a possible pathway for osteoarthritis pathology
FJ Blanco, R Guitian, E Vázquez‐Martul… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To determine which kind of cell death occurs in cartilage from patients with
osteoarthritis (OA). Methods Seven normal and 16 OA cartilage samples were collected at …
osteoarthritis (OA). Methods Seven normal and 16 OA cartilage samples were collected at …