5-aza-2ʹ-Deoxycytidine, a DNA methyltransferase inhibitor, facilitates the inorganic phosphorus-induced mineralization of vascular smooth muscle cells
T Azechi, F Sato, R Sudo, H Wachi - Journal of atherosclerosis and …, 2014 - jstage.jst.go.jp
Aim: Vascular calcification, an independent risk factor for cardiovascular disease in patients
with chronic kidney disease (CKD), refers to the mineralization of vascular smooth muscle …
with chronic kidney disease (CKD), refers to the mineralization of vascular smooth muscle …
Roles of histone acetylation modifiers and other epigenetic regulators in vascular calcification
Vascular calcification (VC) is characterized by calcium deposition inside arteries and is
closely associated with the morbidity and mortality of atherosclerosis, chronic kidney …
closely associated with the morbidity and mortality of atherosclerosis, chronic kidney …
Trichostatin A, an HDAC class I/II inhibitor, promotes Pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase
T Azechi, D Kanehira, T Kobayashi, R Sudo… - … of atherosclerosis and …, 2013 - jstage.jst.go.jp
Aim: Vascular calcification, a major complication of chronic kidney disease (CKD), refers to
the mineralization of vascular smooth muscle cells (VSMCs), resulting from a phenotypic …
the mineralization of vascular smooth muscle cells (VSMCs), resulting from a phenotypic …
High‐phosphate‐induced calcification is related to SM22α promoter methylation in vascular smooth muscle cells
AM De Oca, JA Madueno… - Journal of Bone and …, 2010 - academic.oup.com
Hyperphosphatemia is closely related to vascular calcification in patients with chronic kidney
disease. Vascular smooth muscle cells (VSMCs) exposed to high phosphate concentrations …
disease. Vascular smooth muscle cells (VSMCs) exposed to high phosphate concentrations …
[HTML][HTML] Role of cytosolic serine hydroxymethyl transferase 1 (SHMT1) in phosphate-induced vascular smooth muscle cell calcification
B Boehme, N Schelski, M Makridakis, L Henze… - Kidney and Blood …, 2018 - karger.com
Background/Aims: Hyperphosphatemia promotes medial vascular calcification, at least
partly, by induction of osteo-/chondrogenic transdifferentiation of vascular smooth muscle …
partly, by induction of osteo-/chondrogenic transdifferentiation of vascular smooth muscle …
Azelnidipine inhibits Msx2-dependent osteogenic differentiation and matrix mineralization of vascular smooth muscle cells
T Shimizu, T Tanaka, T Iso, K Kawai-Kowase… - International Heart …, 2012 - jstage.jst.go.jp
Vascular calcification is an active and regulated process that is similar to bone formation.
While calcium channel blockers (CCBs) have been shown to improve outcomes in …
While calcium channel blockers (CCBs) have been shown to improve outcomes in …
Phosphate regulation of vascular smooth muscle cell calcification
Vascular calcification is a common finding in atherosclerosis and a serious problem in
diabetic and uremic patients. Because of the correlation of hyperphosphatemia and vascular …
diabetic and uremic patients. Because of the correlation of hyperphosphatemia and vascular …
Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells
Vascular calcification is a frequent complication of atherosclerosis, diabetes and chronic
kidney disease. In the latter group of patients, calcification is commonly seen in tunica media …
kidney disease. In the latter group of patients, calcification is commonly seen in tunica media …
[HTML][HTML] Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the Wnt/β-catenin pathway
S Rong, X Zhao, X Jin, Z Zhang, L Chen… - Cellular Physiology and …, 2014 - karger.com
Background: Vascular calcification (VC), in which vascular smooth muscle cells (VSMCs)
undergo a phenotypic transformation into osteoblast-like cells, is one of the emergent risk …
undergo a phenotypic transformation into osteoblast-like cells, is one of the emergent risk …
DNMT1 and HDAC2 cooperate to facilitate aberrant promoter methylation in inorganic phosphate-induced endothelial-mesenchymal transition
X Tan, X Xu, M Zeisberg, EM Zeisberg - PLoS One, 2016 - journals.plos.org
While phosphorus in the form of inorganic or organic phosphate is critically involved in most
cellular functions, high plasma levels of inorganic phosphate levels have emerged as …
cellular functions, high plasma levels of inorganic phosphate levels have emerged as …