Bladder outlet obstruction (BOO) is a common disease that always make the bladder
develops from inflammation to fibrosis. This study was to investigate the effect of exosomes …

Partial bladder outlet obstruction (pBOO) often results in bladder tissue inflammation and
remodeling. As human urine-derived stem cells (USCs) have demonstrated therapeutic …

Background Urethral stricture (US) is a major challenge in urology and there is an urgent
need for effective therapies for its treatment. Exosomes derived from bone marrow …

Bladder outlet obstruction (BOO) can cause serious complications including kidney damage;
nevertheless, there are currently no animal models for studying BOO-induced kidney …

Bone marrow‐derived mesenchymal stem cells (BMSCs) can alleviate pelvic floor
dysfunction (PFD) in rats. Whether exosomes derived from miR‐195‐5p transfected BMSCs …

The effective treatment of urethral stricture remains a medical problem. The use of
proinflammatory cytokines as stimuli to improve the reparative efficacy of mesenchymal stem …

There is still a lack of sufficient research on the mechanism behind neurogenic bladder (NB)
treatment. The aim of this study was to explore the effect of overexpressed stromal cell …

Exosomes, carriers to transfer endogenous molecules, derived from bone marrow-derived
mesenchymal stem cells (BMSCs) have been reported to play a role in the progression of …

Methods and Results: Exos isolated from SIRT1-overexpressing BMSCs (SIRT1/exos) were
injected into a vaginal dilation-induced rat model of Stress urinary incontinence (SUI). The …

Background Previous studies revealed that urine-derived stem cells (USCs) could promote
myogenesis after the impairment of the sphincter muscles. However, the effects of exosomes …