A de novo missense mutation in MPP2 confers an increased risk of Vogt–Koyanagi–Harada disease as shown by trio-based whole-exome sequencing
X Liu, J Meng, X Liao, Y Liu, Q Zhou, Z Xu… - Cellular & Molecular …, 2023 - nature.com
Abstract Vogt–Koyanagi–Harada (VKH) disease is a leading cause of blindness in young
and middle-aged people. However, the etiology of VKH disease remains unclear. Here, we …
and middle-aged people. However, the etiology of VKH disease remains unclear. Here, we …
OR11H1 Missense Variant Confers the Susceptibility to Vogt‒Koyanagi‒Harada Disease by Mediating Gadd45g Expression
X Li, G Wang, X Wang, W Li, N Li, X Liu… - Advanced …, 2024 - Wiley Online Library
Abstract Vogt‒Koyanagi‒Harada (VKH) disease is a severe autoimmune disease. Herein,
whole‐exome sequencing (WES) study are performed on 2,573 controls and 229 VKH …
whole‐exome sequencing (WES) study are performed on 2,573 controls and 229 VKH …
iPSC-based model of Vogt-Koyanagi-Harada disease for phenotype recapitulation and drug screening
W Li, J Tan, S He, Y Yue, H Liu, R Li, X Wang… - Clinical …, 2023 - Elsevier
Abstract Vogt-Koyanagi-Harada (VKH) disease, a major blinding eye disease, is
characterized by an autoimmune response against melanocytes in multiple organs …
characterized by an autoimmune response against melanocytes in multiple organs …
Association of human leukocyte antigen (HLA)-DQ and HLA-DQA1/DQB1 alleles with Vogt–Koyanagi–Harada disease: a systematic review and meta-analysis
B Liu, T Deng, L Zhu, J Zhong - Medicine, 2018 - journals.lww.com
Objective: The aim of this study was to evaluate the association of human leukocyte antigen
(HLA)-DQ and HLA-DQA1/DQB1 alleles with Vogt–Koyanagi–Harada (VKH), providing …
(HLA)-DQ and HLA-DQA1/DQB1 alleles with Vogt–Koyanagi–Harada (VKH), providing …
Genetic landscape and autoimmunity of monocytes in developing Vogt–Koyanagi–Harada disease
Y Hu, Y Hu, Y Xiao, F Wen, S Zhang… - Proceedings of the …, 2020 - National Acad Sciences
Vogt–Koyanagi–Harada (VKH) disease is a systemic autoimmune disorder affecting multiple
organs, including eyes, skin, and central nervous system. It is known that monocytes …
organs, including eyes, skin, and central nervous system. It is known that monocytes …
Influence of molecular genetics in Vogt-Koyanagi-Harada disease
Abstract Vogt-Koyanagi-Harada (VKH) disease is a systemic autoimmune disorder against
melanocytes. Recent studies have identified multiple genetic factors that might be …
melanocytes. Recent studies have identified multiple genetic factors that might be …
Variants in IL23R-C1orf141 and ADO-ZNF365-EGR2 are associated with susceptibility to Vogt-Koyanagi-Harada disease in Japanese population
T Sakono, A Meguro, M Takeuchi, T Yamane… - PloS one, 2020 - journals.plos.org
Vogt-Koyanagi-Harada (VKH) disease is a systemic inflammatory disorder that affects
pigment cell-containing organs such as the eye (eg, chronic and/or recurrent granulomatous …
pigment cell-containing organs such as the eye (eg, chronic and/or recurrent granulomatous …
Association of ZC3HAV1 single nucleotide polymorphisms with the susceptibility of Vogt-Koyanagi-Harada Disease
Q Wu, Z Zhong, C Zhou, Q Cao, G Su, P Yang - BMC Medical Genomics, 2023 - Springer
Background Polymorphisms of genes related to the immune response have been reported
to confer susceptibility to Vogt-Koyanagi-Harada (VKH) disease. This study was carried out …
to confer susceptibility to Vogt-Koyanagi-Harada (VKH) disease. This study was carried out …
Chromatin accessibility analysis reveals regulatory dynamics and therapeutic relevance of Vogt-Koyanagi-Harada disease
W Shi, J Ye, Z Shi, C Pan, Q Zhang, Y Lin… - Communications …, 2022 - nature.com
The barrier to curing Vogt–Koyanagi–Harada disease (VKH) is thought to reside in a lack of
understanding in the roles and regulations of peripheral inflammatory immune cells. Here …
understanding in the roles and regulations of peripheral inflammatory immune cells. Here …
Replication of genome-wide association analysis identifies new susceptibility loci at long noncoding RNA regions for Vogt-Koyanagi-Harada disease
J Qi, L Du, J Deng, Y Qin, G Su, S Hou… - … & Visual Science, 2019 - iovs.arvojournals.org
Purpose: This study was aimed at investigating the association of long noncoding RNA
(lncRNA)–related single nucleotide polymorphisms (SNPs) with Vogt-Koyanagi-Harada …
(lncRNA)–related single nucleotide polymorphisms (SNPs) with Vogt-Koyanagi-Harada …
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