[HTML][HTML] Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors
Many viruses utilize the host endo-lysosomal network for infection. Tracing the endocytic
itinerary of SARS-CoV-2 can provide insights into viral trafficking and aid in designing new …
itinerary of SARS-CoV-2 can provide insights into viral trafficking and aid in designing new …
[HTML][HTML] SARS-CoV-2 cellular entry is independent of the ACE2 cytoplasmic domain signaling
T Karthika, J Joseph, VRA Das, N Nair, P Charulekha… - Cells, 2021 - mdpi.com
Recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV)-1 and-2
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
Cell entry mechanisms of SARS-CoV-2
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) is
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …
Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro
B Mao, VTK Le-Trilling, K Wang… - Emerging Microbes & …, 2022 - Taylor & Francis
ABSTRACT Coronavirus disease 2019 (COVID-19) caused by the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has set off a global pandemic. There is …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has set off a global pandemic. There is …
[HTML][HTML] Inhibition of SARS-CoV-2 viral entry upon blocking N-and O-glycan elaboration
The Spike protein of SARS-CoV-2, its receptor-binding domain (RBD), and its primary
receptor ACE2 are extensively glycosylated. The impact of this post-translational …
receptor ACE2 are extensively glycosylated. The impact of this post-translational …
[HTML][HTML] The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry
J Zhang, F Huang, B Xia, Y Yuan, F Yu… - … and Targeted Therapy, 2021 - nature.com
Since the outbreak of coronavirus disease 2019 (COVID-19), it has become a global
pandemic. The spike (S) protein of etiologic severe acute respiratory syndrome coronavirus …
pandemic. The spike (S) protein of etiologic severe acute respiratory syndrome coronavirus …
Targeting the viral‐entry facilitators of SARS‐CoV‐2 as a therapeutic strategy in COVID‐19
S Muralidar, G Gopal… - Journal of Medical …, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is the causative agent of
coronavirus disease 2019 (COVID‐19) infection, which has emerged as a global pandemic …
coronavirus disease 2019 (COVID‐19) infection, which has emerged as a global pandemic …
Discovery and evaluation of entry inhibitors for SARS-CoV-2 and its emerging variants
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the coronavirus disease 19 (COVID-19) pandemic. Despite unprecedented …
responsible for the coronavirus disease 19 (COVID-19) pandemic. Despite unprecedented …
Increasing host cellular receptor—angiotensin-converting enzyme 2 (ACE2) expression by coronavirus may facilitate 2019-nCoV infection
PH Wang, Y Cheng - BioRxiv, 2020 - biorxiv.org
The ongoing outbreak of a new coronavirus (2019-nCoV) causes an epidemic of acute
respiratory syndrome in humans. 2019-nCoV rapidly spread to national regions and multiple …
respiratory syndrome in humans. 2019-nCoV rapidly spread to national regions and multiple …
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells
L Miao, C Yan, Y Chen, W Zhou, X Zhou, Q Qiao… - Cell chemical …, 2023 - cell.com
It is urgent to understand the infection mechanism of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) for the prevention and treatment of COVID-19. The infection of …
coronavirus 2 (SARS-CoV-2) for the prevention and treatment of COVID-19. The infection of …
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