Obesity pathogenesis: an endocrine society scientific statement

MW Schwartz, RJ Seeley, LM Zeltser… - Endocrine …, 2017 - academic.oup.com
Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

Regulation of food intake, energy balance, and body fat mass: implications for the pathogenesis and treatment of obesity

SJ Guyenet, MW Schwartz - The Journal of Clinical …, 2012 - academic.oup.com
Context: Obesity has emerged as one of the leading medical challenges of the 21st century.
The resistance of this disorder to effective, long-term treatment can be traced to the fact that …

The science of obesity management: an endocrine society scientific statement

GA Bray, WE Heisel, A Afshin, MD Jensen… - Endocrine …, 2018 - academic.oup.com
The prevalence of obesity, measured by body mass index, has risen to unacceptable levels
in both men and women in the United States and worldwide with resultant hazardous health …

[图书][B] Handbook of Obesity--Volume 1: Epidemiology, Etiology, and Physiopathology

GA Bray - 2014 - books.google.com
In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Minireview: human obesity—lessons from monogenic disorders

S O'Rahilly, IS Farooqi, GSH Yeo, BG Challis - Endocrinology, 2003 - academic.oup.com
Genetic influences on the determination of human fat mass are profound and powerful, a
statement that does not conflict with the obvious influence of environmental factors that drive …

Understanding and addressing the epidemic of obesity: an energy balance perspective

JO Hill - Endocrine reviews, 2006 - academic.oup.com
The intent of this paper is to address the obesity epidemic, which is a term used to describe
the sudden and rapid increase in obesity rates that began in the 1980s and continues …

[HTML][HTML] Definitions, classification, and epidemiology of obesity

JQ Purnell - 2015 - europepmc.org
Recent research has established the physiology of weight regulation, the pathophysiology
that leads to unwanted weight gain with establishment of a higher body-weight set point, and …

Recent advances in basic obesity research

JA Yanovski, SZ Yanovski - Jama, 1999 - jamanetwork.com
MORE THAN 50% OF US ADULTS are overweight, with a body mass index of more than 25
kg/m2 (calculated as weight in kilograms divided by the square of height in meters). 1 Even …

Mechanisms, pathophysiology, and management of obesity

SB Heymsfield, TA Wadden - New England Journal of Medicine, 2017 - Mass Medical Soc
Obesity is prevalent in the US population and contributes significantly to morbidity and
mortality. Treatments include behavioral therapy, pharmacotherapy, and bariatric surgery …

Obesity: global epidemiology and pathogenesis

M Blüher - Nature Reviews Endocrinology, 2019 - nature.com
The prevalence of obesity has increased worldwide in the past~ 50 years, reaching
pandemic levels. Obesity represents a major health challenge because it substantially …