Gastric Helicobacter pylori infection affects local and distant microbial populations and host responses

S Kienesberger, LM Cox, A Livanos, XS Zhang… - Cell reports, 2016 - cell.com
Helicobacter pylori is a late-in-life human pathogen with potential early-life benefits.
Although H. pylori is disappearing from the human population, little is known about the …

The degree of Helicobacter pylori-triggered inflammation is manipulated by preinfection host microbiota

AS Rolig, C Cech, E Ahler, JE Carter… - Infection and …, 2013 - Am Soc Microbiol
Helicobacter pylori infects over 3 billion people worldwide and is the primary risk factor for
gastric cancer. Most individuals infected with H. pylori develop only asymptomatic gastritis; …

Helicobacter pylori Persistence: an Overview of Interactions between H. pylori and Host Immune Defenses

HMS Algood, TL Cover - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of
the global human population. In order to successfully colonize the human stomach, H. pylori …

The Impact of Helicobacter pylori Infection on the Gastric Microbiota of the Rhesus Macaque

ME Martin, S Bhatnagar, MD George, BJ Paster… - PloS one, 2013 - journals.plos.org
Helicobacter pylori colonization is highly prevalent among humans and causes significant
gastric disease in a subset of those infected. When present, this bacterium dominates the …

Chronic Helicobacter pylori Infection Does Not Significantly Alter the Microbiota of the Murine Stomach

MP Tan, M Kaparakis, M Galic, J Pedersen… - Applied and …, 2007 - Am Soc Microbiol
We examined the impact of Helicobacter pylori infection on the murine gastric microbiota by
culture and terminal-restriction fragment length polymorphism and found that neither acute …

The Immunomodulatory Properties of Helicobacter pylori Confer Protection Against Allergic and Chronic Inflammatory Disorders

IC Arnold, I Hitzler, A Müller - Frontiers in cellular and infection …, 2012 - frontiersin.org
Chronic infection with the gastric bacterial pathogen Helicobacter pylori causes gastritis and
predisposes carriers to a high risk of developing gastric and duodenal ulcers, gastric cancer …

Mechanisms of persistence, innate immune activation and immunomodulation by the gastric pathogen Helicobacter pylori

X Zhang, IC Arnold, A Müller - Current opinion in microbiology, 2020 - Elsevier
The gastric bacterium Helicobacter pylori efficiently evades innate immune detection and
persistently colonizes its human host. Understanding the genetic determinants that H. pylori …

H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection

A Müller, M Oertli, IC Arnold - Cell Communication and Signaling, 2011 - Springer
Persistent infection with the gastric bacterial pathogen Helicobacter pylori causes gastritis
and predisposes carriers to a high gastric cancer risk, but has also been linked to protection …

Impact of the gastrointestinal microbiome in health and disease: co-evolution with the host immune system

GL Hold, R Hansen - … of inflammation: Induction, resolution and escape by …, 2019 - Springer
Microbes within the gastrointestinal tract communicate with each other and with the host,
which has profound effects on health and disease development. Only now, it is becoming …

Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature

A Ralser, A Dietl, S Jarosch, V Engelsberger… - Gut, 2023 - gut.bmj.com
Objective Helicobacter pylori infection is the most prevalent bacterial infection worldwide.
Besides being the most important risk factor for gastric cancer development, epidemiological …