At least 5% of cancer diagnoses are attributed to a causal pathogenic or likely pathogenic
germline genetic variant (hereditary cancer syndrome—HCS). These individuals are …

At least 5% of cancer diagnoses are attributed to a causal pathogenic or likely pathogenic
germline genetic variant (hereditary cancer syndrome—HCS). These individuals are …

Historically, professional society guidelines have recommended limited genetic testing for
hereditary cancer syndromes (HCS) to patients with cancer thought to be at highest risk for …

Mutations in hereditary cancer syndromes account for a modest fraction of all cancers;
however, identifying patients with these germline mutations offers tremendous health …

PURPOSE It has been estimated that 5% to 10% of cancers are due to hereditary causes.
Recent data sets indicate that the incidence of hereditary cancer may be as high as 17.5% in …

This news section is written by a medical journalist and offers Cancer Cytopathology readers
timely information on events, issues, and personalities of interest to the subspecialty. In this …

Approximately 5%-10% of all cancer is due to hereditary causes. Over the last 2 decades,
the ability to detect genes responsible for hereditary cancers has dramatically improved, and …

Germline testing for hereditary cancer predisposition has become increasingly important in
the management of patients with cancer. Recent studies have demonstrated that hereditary …

The prevalence of genetic predisposition to cancer is greater than initially appreciated, yet
most affected individuals remain undiagnosed. Deleterious germline variants in cancer …

The clinical translation of the significance of cancer “running in families” has become a
source of major contention as a result of the explosion of knowledge about cancer causality …