Aims Cardiogenic shock (CS) with variable systemic inflammation may be responsible for
patient heterogeneity and the exceedingly high mortality rate. Cardiovascular events have …

Background Clonal hematopoiesis of indeterminate potential (CHIP) is common in elderly
individuals and is associated with an increased risk of both hematologic malignancies and …

Heart failure is a common disease with poor prognosis that is associated with cardiac
immune cell infiltration and dysregulated cytokine expression. Recently, the clonal …

Background Clonal hematopoiesis (CH) gives rise to mutated leukocyte clones that induce
cardiovascular inflammation and thereby impact the disease course in atherosclerosis and …

BACKGROUND: Clonal hematopoiesis (CH), which results from an array of nonmalignant
driver gene mutations, can lead to altered immune cell function and chronic disease, and …

Background Clonal hematopoiesis driven by somatic mutations in hematopoietic cells,
frequently called clonal hematopoiesis of indeterminate potential (CHIP), has been …

Importance Somatic mutations causing clonal expansion of hematopoietic cells (clonal
hematopoiesis of indeterminate potential [CHIP]) are increased with age and associated …

Objectives: This study investigated whether reduced levels of circulating endothelial
progenitors cells (EPCs) in chronic heart failure (CHF) are secondary to an exhaustion of …

Clonal hematopoiesis of indeterminate potential (CHIP) is defined as a clonal outgrowth of
hematopoietic cells with mutations in a restricted set of cancer driver genes in patients …

Aims Somatic mutations in haematopoietic stem cells can lead to the clonal expansion of
mutated blood cells, known as clonal haematopoiesis (CH). Mutations in the most prevalent …