Expression of DNA repair and metabolic genes in response to a flavonoid-rich diet

S Guarrera, C Sacerdote, L Fiorini, R Marsala… - British journal of …, 2007 - cambridge.org
A diet rich in fruit and vegetables can be effective in the reduction of oxidative stress, through
the antioxidant effects of phytochemicals and other mechanisms. Protection against the …

Randomized controlled trial of dietary intervention: association between level of urinary phenolics and anti-mutagenicity

C Malaveille, L Fiorini, M Bianchini, L Davico… - … /Genetic Toxicology and …, 2004 - Elsevier
We have undertaken a randomized trial to confirm the ability of a class of phenolics,
flavonoids, to increase urinary anti-mutagenicity in smokers. Ninety heavy smokers were …

DNA damage and repair activity after broccoli intake in young healthy smokers

P Riso, D Martini, P Møller, S Loft, G Bonacina… - …, 2010 - academic.oup.com
Cruciferous vegetables contain compounds with antioxidant properties (eg carotenoids,
vitamin C and folates) and can alter the activity of xenobiotic metabolism (ie …

Effect of dietary quercetin on oxidative DNA damage in healthy human subjects

ER Beatty, JD O'Reilly, TG England… - British Journal of …, 2000 - cambridge.org
The effect of dietary intake of flavonols (predominantly quercetin) on oxidative DNA damage
was studied in thirty-six healthy human subjects (sixteen men, twenty women). The study …

Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers

LC Wilms, AW Boots, VCJ De Boer, LM Maas… - …, 2007 - academic.oup.com
Consumption of fruits and vegetables has been associated with a decrease in cancer
incidence and cardiovascular disease, presumably caused by antioxidants. We designed a …

Dietary flavonoids protect human colonocyte DNA from oxidative attack in vitro

SJ Duthie, VL Dobson - European journal of nutrition, 1999 - Springer
Summary Background & Aims: Epidemiological studies suggest that antioxidant polyphenols
in the human diet may protect against diseases such as cancer. In this study we investigated …

DNA repair phenotype and dietary antioxidant supplementation

S Guarnieri, S Loft, P Riso, M Porrini… - British Journal of …, 2008 - cambridge.org
Phytochemicals may protect cellular DNA by direct antioxidant effect or modulation of the
DNA repair activity. We investigated the repair activity towards oxidised DNA in human …

To investigate the antioxidant properties of dietary flavonoids in human metabolism.

AR Abdelmoemin - 2005 - elibrary.ru
Flavonoids are a large group of phenolic compounds found ubiquitously in plants and
consumed as part of the human diet. They are known to be potent antioxidants, free radical …

Inter-individual variation in DNA damage and base excision repair in young, healthy non-smokers: effects of dietary supplementation and genotype

F Caple, EA Williams, A Spiers, J Tyson… - British journal of …, 2010 - cambridge.org
Diets rich in fruits and vegetables are associated with lower risk of cancer which may be
conferred in part by the antioxidant properties of these foods. However, antioxidant …

Oxidative DNA damage in circulating mononuclear blood cells after ingestion of blackcurrant juice or anthocyanin-rich drink

P Møller, S Loft, G Alfthan, R Freese - Mutation Research/Fundamental and …, 2004 - Elsevier
Berry extracts possess antioxidant activity in cell free systems, whereas cell culture and
animal experimental systems have produced mixed outcomes. Our aim was to investigate …