[HTML][HTML] Immunoporosis: role of innate immune cells in osteoporosis

Y Saxena, S Routh, A Mukhopadhaya - Frontiers in immunology, 2021 - frontiersin.org
Osteoporosis or porous bone disorder is the result of an imbalance in an otherwise highly
balanced physiological process known as 'bone remodeling'. The immune system is …

[HTML][HTML] Immunoporosis: Role of immune system in the pathophysiology of different types of osteoporosis

W Zhang, R Gao, X Rong, S Zhu, Y Cui… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone
microarchitecture, with an increased risk of fractures. Classical theories hold that …

The rising era of “Immunoporosis”: Role of immune system in the pathophysiology of osteoporosis

RK Srivastava, L Sapra - Journal of Inflammation Research, 2022 - Taylor & Francis
Discoveries in the last few years have emphasized the existence of an enormous breadth of
communication between bone and the immune system in maintaining skeletal homeostasis …

[HTML][HTML] Immunoporosis: immunology of osteoporosis—role of T cells

RK Srivastava, HY Dar, PK Mishra - Frontiers in immunology, 2018 - frontiersin.org
The role of immune system in various bone pathologies, such as osteoporosis, osteoarthritis,
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …

Macrophage polarization and the regulation of bone immunity in bone homeostasis

K Hu, Z Shang, X Yang, Y Zhang… - Journal of Inflammation …, 2023 - Taylor & Francis
Bone homeostasis is a dynamic equilibrium state of bone formation and absorption,
ensuring skeletal development and repair. Bone immunity encompasses all aspects of the …

[HTML][HTML] Macrophage-osteoclast associations: origin, polarization, and subgroups

Y Sun, J Li, X Xie, F Gu, Z Sui, K Zhang… - Frontiers in …, 2021 - frontiersin.org
Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …

The interplay between the bone and the immune system

G Mori, PD′ Amelio, R Faccio… - Journal of Immunology …, 2013 - Wiley Online Library
In the last two decades, numerous scientists have highlighted the interactions between bone
and immune cells as well as their overlapping regulatory mechanisms. For example …

[HTML][HTML] Interaction between bone and immune cells: Implications for postmenopausal osteoporosis

V Fischer, M Haffner-Luntzer - Seminars in cell & developmental biology, 2022 - Elsevier
Postmenopausal osteoporosis is a systemic disease characterized by the loss of bone mass
and increased bone fracture risk largely resulting from significantly reduced levels of the …

[HTML][HTML] T-cell mediated inflammation in postmenopausal osteoporosis

D Wu, A Cline-Smith, E Shashkova, A Perla… - Frontiers in …, 2021 - frontiersin.org
Osteoporosis is the most prevalent metabolic bone disease that affects half the women in the
sixth and seventh decade of life. Osteoporosis is characterized by uncoupled bone …

[HTML][HTML] From crosstalk between immune and bone cells to bone erosion in infection

G Kumar, PM Roger - International Journal of Molecular Sciences, 2019 - mdpi.com
Bone infection and inflammation leads to the infiltration of immune cells at the site of
infection, where they modulate the differentiation and function of osteoclasts and osteoblasts …