Uncovering mechanisms underlying fetal programming during pregnancy is of critical
importance. Atypical neurodevelopment during the pre-and immediate postnatal period has …

Recent studies demonstrate that exposure to stress changes the composition of the
intestinal microbiota, which is associated with development of stress-induced changes to …

The maternal microbiota is positioned to regulate the development of offspring immunity,
metabolism, as well as brain function and behavior. The mechanisms by which maternal …

Abstract Perinatal Mood and Anxiety Disorders (PMAD) are common and can cause
significant morbidity and mortality for mother and child. A healthy perinatal period requires …

Perturbations in the prenatal and early life environment can contribute to the development of
offspring stress dysregulation, a pervasive symptom in neuropsychiatric disease …

The body is colonized by an enormous array of microbes that are collectively called the
microbiota. During quiescent periods, microbial communities within the gut are relatively …

Highlights•Stressful events during the perinatal period are associated with dysbiosis in the
offspring.•Stress in early life can impact the development and functioning of the …

Maternal health status is vital for the development of the offspring of humans, including
physiological health and psychological functions. The complex and diverse microbial …

Maternal obesity is known to predispose offspring to metabolic and neurodevelopmental
abnormalities. While the mechanisms underlying these phenomena are unclear, high fat …

Early exposure to stressful and adverse life events at fetal and neonatal stages is one of
crucial risk factors for mood disorders such as anxiety and depressive disorder in adulthood …