Helix Geometry, Hydration, and G⋅ A Mismatch in a B-DNA Decamer

GG Privé, U Heinemann, S Chandrasegaran, LS Kan… - Science, 1987 - science.org
The DNA double helix is not a regular, featureless barberpole molecule. Different base
sequences have their own special signature, in the way that they influence groove width …

Design of sequence-specific DNA-binding molecules

PB Dervan - Science, 1986 - science.org
Base sequence information can be stored in the local structure of right-handed double-
helical DNA (B-DNA). The question arises as to whether a set of rules for the three …

"... the tyranny of the lattice...".

RE Dickerson, DS Goodsell… - Proceedings of the …, 1994 - National Acad Sciences
A systematic comparison of crystal structures of nine different B-DNA dodecamers, in three
different space groups, with and without A-tracts, shows that crystal packing or lattice forces …

The anatomy of a-, b-, and z-dna

RE Dickerson, HR Drew, BN Conner, RM Wing… - Science, 1982 - science.org
Recent advances in DNA synthesis methods have made it possible to carry out single-
crystal x-ray analyses of double-stranded DNA molecules of predetermined sequence, with …

Parallel stranded DNA

JH Van De Sande, NB Ramsing, MW Germann… - Science, 1988 - science.org
A series of four hairpin deoxyoligonucleotides was synthesized with a four-nucleotide
central loop (either C or G) flanked by the complementary sequences d (T) 10 and d (A) 10 …

Structure of an alternating-B DNA helix and its relationship to A-tract DNA.

C Yoon, GG Privé, DS Goodsell… - Proceedings of the …, 1988 - National Acad Sciences
The crystal structure of the synthetic DNA dodecamer CGCATATATGCG has been solved at
2.2-A resolution. Its central 6 base pairs adopt the alternating-B-DNA helix structure …

Structure of a B-DNA dodecamer: II. Influence of base sequence on helix structure

RE Dickerson, HR Drew - Journal of molecular biology, 1981 - Elsevier
Detailed examination of the structure of the B-DNA dodecamer CGCGAATTCGCG, obtained
by single-crystal X-ray analysis (Drew et al., 1981), reveals that the local helix parameters …

Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG.

AV Fratini, ML Kopka, HR Drew… - Journal of Biological …, 1982 - ASBMB
A double-helical B-DNA dodecamer has been analyzed by single crystal x-ray diffraction
methods and refined independently in four variants: sequence CGCGAATTCGCG at 20 …

Crystal structure analysis of a complete turn of B-DNA

R Wing, H Drew, T Takano, C Broka, S Tanaka… - Nature, 1980 - nature.com
DNA is probably the most discussed and least observed of all biological macromolecules.
Although its role in biology is a central one, with many examples such as operators and …

Structure of a B-DNA dodecamer: conformation and dynamics.

HR Drew, RM Wing, T Takano… - Proceedings of the …, 1981 - National Acad Sciences
The crystal structure of the synthetic DNA dodecamer d (CpGpCpGpApApTpTpCpGpCpG)
has been refined to a residual error of R= 17.8% at 1.9-A resolution (two-sigma data). The …