Background Laboratory tests for routine drug of abuse and toxicology (DOA/Tox) screening,
often used in emergency medicine, generally utilize antibody-based tests (immunoassays) …

Background: Immunoassays used for routine drug of abuse (DOA) and toxicology screening
may be limited by cross-reacting compounds able to bind to the antibodies in a manner …

Although rapid bedside toxicological screening is reliable, it has not been validated in the
emergency department (ED) setting. We assessed the accuracy of a 10-min bedside …

Context.—Urine drug testing is frequently ordered by health care providers. Immunoassays
are widely used for drug testing, yet have potential limitations, including variable cross …

PRIMARY OBJECTIVE: To replace immunoassay screening for drugs of abuse (DOA) with a
cost-effective tandem mass spectrometry method. SECONDARY OBJECTIVE: To …

Introduction. The increasing abuse of amphetamine-like compounds presents a challenge
for clinicians and clinical laboratories. Although these compounds may be identified by mass …

Urine drug testing by immunoassay is widely used to detect nonmedical drug use and to
monitor patients prescribed controlled substances. A key attribute of urine drug testing …

Background: The analytic performance and accuracy of drug detection below Substance
Abuse and Mental Health Services Administration (SAMHSA) cutoffs is not well known. In …

BACKGROUND Exposure to drugs of abuse is frequently assessed using urine drug
screening (UDS) immunoassays. Although fast and relatively inexpensive, UDS assays …

Background A challenge for drug of abuse testing is presented by 'designer drugs',
compounds typically discovered by modifications of existing clinical drug classes such as …