[HTML][HTML] Targeting multiple mediators of sepsis using multifunctional tannic acid-Zn2+-gentamicin nanoparticles
Treatments that target single mediators of sepsis have failed to reduce its high mortality rate.
Here we developed multifunctional tannic acid-Zn 2+-gentamicin nanoparticles (TA-Zn-Gen …
Here we developed multifunctional tannic acid-Zn 2+-gentamicin nanoparticles (TA-Zn-Gen …
A multifunctional nanoparticle mitigating cytokine storm by scavenging multiple inflammatory mediators of sepsis
Z Li, Y Feng, S Zhang, T Li, H Li, D Wang, K Hao… - ACS …, 2023 - ACS Publications
Sepsis is a disease caused by infection, which is characterized by a dysregulated immune
response in the host and affects more than 30 million people worldwide each year …
response in the host and affects more than 30 million people worldwide each year …
[HTML][HTML] Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis
X Wang, Z Xia, H Wang, D Wang, T Sun, E Hossain… - Theranostics, 2023 - ncbi.nlm.nih.gov
Sepsis is the main cause of death in patients suffering from serious illness. Yet, there is still
no specific treatment for sepsis, and management relies on infection control. Cell membrane …
no specific treatment for sepsis, and management relies on infection control. Cell membrane …
Robust and Multifunctional Therapeutic Nanoparticles against Peritonitis-Induced Sepsis
Apart from bacterial growth and endotoxin generation, the excessive production of reactive
radicals linked with sepsis also has a substantial impact on triggering an inflammatory …
radicals linked with sepsis also has a substantial impact on triggering an inflammatory …
A cationic metal–organic framework to scavenge cell-free DNA for severe sepsis management
Circulating cell-free DNA (cfDNA) released by damaged cells causes inflammation and has
been associated with the progression of sepsis. One proposed strategy to treat sepsis is to …
been associated with the progression of sepsis. One proposed strategy to treat sepsis is to …
[HTML][HTML] NAD (H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis
Sepsis is a life-threatening organ dysfunction responsible for nearly 270,000 deaths
annually in the United States alone. Nicotinamide adenine dinucleotide (NAD+), an …
annually in the United States alone. Nicotinamide adenine dinucleotide (NAD+), an …
Recent advancements of nanomaterial-based therapeutic strategies toward sepsis: bacterial eradication, anti-inflammation, and immunomodulation
Sepsis is a life threatening disease that is caused by a dysregulated host immune response
to infection, resulting in tissue damage and organ dysfunction, which account for a high in …
to infection, resulting in tissue damage and organ dysfunction, which account for a high in …
Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers
Severe sepsis represents a common, expensive, and deadly health care issue with limited
therapeutic options. Gaining insights into the inflammatory dysregulation that causes sepsis …
therapeutic options. Gaining insights into the inflammatory dysregulation that causes sepsis …
Macrophages-regulating nanomedicines for sepsis therapy
J Deng, R Wang, S Huang, J Ding, W Zhou - Chinese Chemical Letters, 2023 - Elsevier
Sepsis is the leading cause of death in intensive care unit (ICU), which is caused by
deregulated immune responses to pathogens infection. Clinically, sepsis treatment is limited …
deregulated immune responses to pathogens infection. Clinically, sepsis treatment is limited …
Recent advances in nanomedicine for sepsis treatment
SA Yuk, DA Sanchez-Rodriguez, MD Tsifansky… - Therapeutic …, 2018 - Taylor & Francis
Sepsis and septic shock are life-threating conditions, which form a continuum of the body's
response to overwhelming infection. The current treatment consists of fluid and metabolic …
response to overwhelming infection. The current treatment consists of fluid and metabolic …