Breast cancer is the second leading cause of cancer death in women. Serum biomarkers
such as cancer antigen 15-3 (CA15-3), cancer antigen 125 (CA125), and carcinoembryonic …

The distinction between breast cancer and benign breast diseases with nipple discharge
remains an important diagnostic challenge. The purpose of this study was to predict the …

Background The aim of this study was to assess the diagnostic values of three breast tumor
markers (ie, CEA, CA153 and CA125) in milk and nipple discharge in the prediction of …

Purpose: Proteomic analysis of breast nipple aspirate fluid (NAF) holds promise as a
noninvasive method to identify markers of breast cancer. The objectives of the study were …

Background Isotope-coded affinity tag (ICAT) tandem mass spectrometry (MS) allows for
qualitative and quantitative analysis of paired protein samples. We sought to determine …

Mammary ductal cells are the origin for 70–80% of breast cancers. Nipple aspirate fluid
(NAF) contains proteins directly secreted by the ductal and lobular epithelium in non …

Detection of serum tumor markers has been developed as a non-invasive tool to assess
treatment efficiency in different types of cancer. This study aims to investigate the role of …

Objectives. Molecular subtypes are employed as a guide for targeted treatment and
important prognostic factors. This study focused on investigating the association of serum …

Objective To explore the application value of breast cancer tumor markers tissue
polypeptide specific antigen (TPS), carbohydrate antigen 15-3 (CA15-3), carcinoembryonic …

Proteomic analysis of body fluids, including breast nipple aspirate fluid (NAF), holds promise
to aid in early cancer detection. We conducted a prospective trial that collected NAF from …