Deletions within genes coding for subunits of the transcription coactivator SAGA caused
strong genome-wide defects in transcription and SAGA-mediated chromatin modifications. In …

The conserved transcription coactivator SAGA is comprised of several modules that are
involved in activator binding, TBP binding, histone acetylation (HAT) and deubiquitination …

TFIID and SAGA share a common set of TAFs, regulate chromatin, and deliver TBP to
promoters. Here we examine their relationship within the context of the Saccharomyces …

The SAGA histone acetyltransferase and TFIID complexes play key roles in eukaryotic
transcription. Using hierarchical cluster analysis of mass spectrometry data to identify …

The SAGA complex of Saccharomyces cerevisiae is required for the transcription of many
RNA polymerase II-dependent genes. Previous studies have demonstrated that SAGA …

Previous studies demonstrated that the SAGA (S pt-A da-G cn5-A cetyltransferase) complex
facilitates the binding of TATA-binding protein (TBP) during transcriptional activation of the …

The Saccharomyces cerevisiae SAGA complex is a multifunctional coactivator that regulates
transcription by RNA polymerase II. The 3D structure of SAGA, revealed by electron …

An important distinction is frequently made between constitutively expressed housekeeping
genes versus regulated genes. Although generally characterized by different DNA elements …

Prior studies suggested that SAGA and TFIID are alternative factors that promote RNA
polymerase II transcription, with about 10% of genes in S. cerevisiae dependent on SAGA …

The SAGA (Spt–Ada–Gcn5 acetyltransferase) coactivator complex contains distinct
chromatin-modifying activities and is recruited by DNA-bound activators to regulate the …