Punctuated episodes of spreading depolarizations erupt in the brain, encumbering tissue
structure and function, and raising fascinating unanswered questions concerning their …

Spreading depolarization is observed as a large negative shift of the direct current potential,
swelling of neuronal somas, and dendritic beading in the brain's gray matter and represents …

Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed
by suppression of brain activity, is a remarkably complex event that involves dramatic …

Cortical spreading depression, a slowly propagating wave of transient neuronal and glial
depolarization, is widely accepted as the electrophysiologic substrate of migraine aura and …

Spreading depression (SD) is a neurophysiological phenomenon characterized by abrupt
changes in intracellular ion gradients and sustained depolarization of neurons. It leads to …

Neuronal cytotoxic edema is the morphological correlate of the near-complete neuronal
battery breakdown called spreading depolarization, or conversely, spreading depolarization …

The term spreading depolarization (SD) refers to waves of abrupt, sustained mass
depolarization in gray matter of the CNS. SD, which spreads from neuron to neuron in …

Since its original extensive description by Leao in 1944, thousands of publications have
characterized the phenomenon of cortical spreading depression (CSD). Despite the …

Spreading depression (SD) is a profound but transient depolarization of neurons and glia
that migrates across the cortical and subcortical gray at 2–5 mm/min. Under normoxic …

Spreading depression (SD) is a slowly propagating wave of near-complete depolarization of
neurons and glial cells across the cortex. SD is thought to contribute to the underlying …