Rationale and objective A causal relationship concerning coffee intake and diabetic
nephropathy (DN) is controversial. We conducted a Mendelian randomization study to …

Rationale & Objective Chronic kidney disease (CKD) is a leading cause of morbidity and
mortality worldwide, with limited strategies for prevention and treatment. Coffee is a complex …

Background: The risk for chronic kidney disease (CKD) is influenced by genetic
predisposition, sex, and lifestyle. Previous research indicates that coffee is a potentially …

Purpose To explore whether coffee intake is associated with the risk of type 2 diabetes
mellitus (T2DM) from a genetic perspective, and whether this association remains the same …

Results Finally, we included the data of 18,436 participants; 6.9% had prevalent CKD
(based on eGFR). Caffeine intake for the general population was 131.1±1.1 mg. The …

Habitual coffee consumption is associated with the prevention of type 2 diabetes, which
often accompanies diabetic nephropathy. However, the relationship between coffee …

Background The association between coffee intake and type 2 diabetes may be modulated
by common genetic variation. Objective The purpose of this study was to examine the …

Background The association between coffee and caffeine consumption and the risk of renal
cell carcinoma was inconsistent among observational studies, and whether these observed …

The association between coffee consumption and the risk of type 2 diabetes may vary by
genetic variants. Our study addresses the question of whether the incidence of type 2 …

RESULTS MR analysis revealed that increased genetically predicted coffee consumption
was associated with a reduced prevalence of T2D; ORs per one-unit increment of log …