The potential molecular markers of inflammatory response in KOA with AD based on single-cell transcriptome sequencing analysis and identification of ligands by …
Y Wu, W Chen, J Jian, W Liu, H Wang, D Gao, W Liu - Molecular Diversity, 2024 - Springer
Alzheimer's disease (AD) and osteoarthritis (OA) are both senile degenerative diseases.
Clinical studies have found that OA patients have a significantly increased risk of AD in their …
Clinical studies have found that OA patients have a significantly increased risk of AD in their …
[HTML][HTML] Bioinformatic analysis combined with immune infiltration to explore osteoarthritis biomarkers and drug prediction
Y Liu, W Jiang, J Huang, L Zhong - Medicine, 2024 - journals.lww.com
Along with global aging, osteoarthritis (OA) appears to have a high incidence and disability
rate, which seriously affects the quality of life of patients, making age a major risk factor …
rate, which seriously affects the quality of life of patients, making age a major risk factor …
Screening of Biomarkers Associated with Osteoarthritis Aging Genes and Immune Correlation Studies
L Xu, Z Wang, G Wang - International Journal of General Medicine, 2024 - Taylor & Francis
Purpose Osteoarthritis (OA) is a joint disease with a long and slow course, which is one of
the major causes of disability in middle and old-aged people. This study was dedicated to …
the major causes of disability in middle and old-aged people. This study was dedicated to …
Analysis of differentially expressed genes associated with alzheimer's disease based on bioinformatics methods
B Feng, P Hu, J Chen, Q Liu, X Li… - American Journal of …, 2015 - journals.sagepub.com
Objective: To screen differentially expressed genes (DEGs) of Alzheimer's disease (AD).
Methods: The gene expression profile (GSE26972) of AD was downloaded from Gene …
Methods: The gene expression profile (GSE26972) of AD was downloaded from Gene …
Identification of aging-related biomarkers and immune infiltration characteristics in osteoarthritis based on bioinformatics analysis and machine learning
JF Zhou, J Huang, ZW Li, QH Song, ZY Yang… - Frontiers in …, 2023 - frontiersin.org
Background Osteoarthritis (OA) is a degenerative disease closely related to aging.
Nevertheless, the role and mechanisms of aging in osteoarthritis remain unclear. This study …
Nevertheless, the role and mechanisms of aging in osteoarthritis remain unclear. This study …
Identification and validation of oxidative stress and immune-related hub genes in Alzheimer's disease through bioinformatics analysis
S Li, J Xiao, C Huang, J Sun - Scientific Reports, 2023 - nature.com
Alzheimer's disease (AD) is the leading cause of dementia in aged population. Oxidative
stress and neuroinflammation play important roles in the pathogenesis of AD. Investigation …
stress and neuroinflammation play important roles in the pathogenesis of AD. Investigation …
Identification of highly reliable risk genes for Alzheimer's disease through joint-tissue integrative analysis
YH Wang, PP Luo, AY Geng, X Li, TH Liu… - Frontiers in Aging …, 2023 - frontiersin.org
Numerous genetic variants associated with Alzheimer's disease (AD) have been identified
through genome-wide association studies (GWAS), but their interpretation is hindered by the …
through genome-wide association studies (GWAS), but their interpretation is hindered by the …
Identification of novel biomarkers and candidate small molecule drugs in rheumatoid arthritis and osteoarthritis based on bioinformatics analysis of high‐throughput …
B Zuo, JF Zhu, F Xiao, CL Wang, Y Shen… - Bioscience …, 2020 - portlandpress.com
Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are two major types of joint
diseases. The present study aimed to identify hub genes involved in the pathogenesis and …
diseases. The present study aimed to identify hub genes involved in the pathogenesis and …
Alzheimer's disease-associated inflammatory pathways might contribute to osteoporosis through the interaction between PROK2 and CSF3
W Zhang, Y Zhang, N Hu, A Wang - Frontiers in Neurology, 2022 - frontiersin.org
This study aimed to explore the potential molecular pathways and targets of Alzheimer's
disease leading to osteoporosis using bioinformatics tools. The Alzheimer's and …
disease leading to osteoporosis using bioinformatics tools. The Alzheimer's and …
Identification of biomarkers associated with diagnosis of osteoarthritis patients based on bioinformatics and machine learning
Y Liang, F Lin, Y Huang - Journal of immunology research, 2022 - Wiley Online Library
Osteoarthritis (OA) is thought to be the most prevalent chronic joint disease. The incidence of
OA is rising because of the ageing population and the epidemic of obesity. This research …
OA is rising because of the ageing population and the epidemic of obesity. This research …