In the developed world, declining prevalence of some parasitic infections correlates with
increased incidence of allergic and autoimmune disorders. Moreover, experimental human …

In the developed world, declining prevalence of parasitic infections correlates with increased
incidence of allergic and autoimmune disorders. Current treatments for these chronic …

The same mechanisms that enable host defense against helminths also drive allergic
inflammation. This suggests that pathomechanisms of allergic diseases represent …

The coincidence between infections with parasitic worms and the reduced prevalence of
allergic disease in humans and in animal models has prompted the search for helminth …

Helminths and their products have a profound immunomodulatory effect upon the inductive
and effector phases of inflammatory responses, including allergy. We have demonstrated …

Severe helminth infections are negatively associated to allergic diseases like asthma;
therefore, the immunomodulatory properties of parasite-derived components have been …

Immunomodulation is a common feature of chronic helminth infections and mainly attributed
to the secretion of bioactive molecules, which target and modify host immune cells. In this …

There has been increasing recognition that the alarming surge in allergy and autoimmunity
in the industrialised and developing worlds shadows the rapid eradication of pathogens …

BACKGROUND: Parasitic helminth infections of humans have been shown to suppress the
immune response to allergens. Experimentally, infection of mice with the helminth …

Allergic diseases are increasing at an alarming rate worldwide, particularly in developed
countries. In contrast, there is a decrease in the prevalence of helminthic infections and …