Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …

Simple Summary Osteosarcoma is the most common cancer of the bone for children and
adolescents. Although chemotherapy regimens have been widely available and effective for …

Simple Summary Osteosarcoma (OS), the most common primary bone tumor, mainly affects
children and adolescents. Unfortunately, in some cases, the absence of response to …

Osteosarcoma is the most common malignant primary bone tumor in children and
adolescents. Current optimal treatment for osteosarcoma consists of multi-agent …

Background Osteosarcoma is a common primary malignant tumour of the bone that usually
occurs in children and adolescents. It is characterised by difficult treatment, recurrence and …

Osteosarcoma is the most common primary malignant bone tumor in children and young
adults. The standard-of-care curative treatment for osteosarcoma utilizes doxorubicin …

For patients with osteosarcoma, the use of chemotherapy has improved survival from 11%
with surgical resection alone in the 1960s, to 70% by the mid-1980s. However, survival has …

Osteosarcoma (OS) is a bone cancer mostly occurring in pediatric population. Current
treatment regime of surgery and intensive chemotherapy could cure about 60%–75 …

High-grade osteosarcomas are the most common primary malignant tumors of bone. With
complete surgical resection and multi-agent chemotherapy up to 70% of patients with high …

Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …