Innovation, structural inspection for new mixed complexes: DNA binding, biomedical applications and molecular docking approaches

FS Aljohani, T El-Dabea, RM El-Khatib… - Journal of Taibah …, 2024 - Taylor & Francis
2-Guanidinobenzimidazole (BIG) and Imidiazole (I) ligands were utilized to synthesize Cu
(II), VO (II), Ag (I), and Pd (II) as mixed ligand complexes. All studied molecules were …

Fabrication, physicochemical characterization and theoretical studies of some new mixed ligands complexes based on N-(1H-benzimidazol-2-yl)-guanidine and 1, 10 …

AM Abu-Dief, T El‐Dabea, RM El-Khatib… - Journal of Molecular …, 2024 - Elsevier
The fabrication and structural identification of mixed ligand chelates resulting from 1-(1H-
benzimidazol-2-yl) guanidine (BIG= main ligand) and 1, 10-Phenanthroline …

Synthesize, structural inspection, stoichiometry in solution and DFT calculation of some novel mixed ligand complexes: DNA binding, biomedical applications and …

AM Abu-Dief, T El‐Dabea, RM El-Khatib… - Journal of Molecular …, 2024 - Elsevier
Mixed ligand chelates of Pd (II), Cu (II), VO (II), and Ag (I) with (BIP= 4, 6-dimethyl-N-
(octahydro-2H-benzimidazol-2-ylidene) pyrimidin-2-amine) as a main ligand and (Phen= 1 …

Fabrication, structural elucidation of some new metal chelates based on N-(1H-Benzoimidazol-2-yl)-guanidine ligand: DNA interaction, pharmaceutical studies and …

AM Abu-Dief, RM El-Khatib, T El‐Dabea… - Journal of Molecular …, 2023 - Elsevier
New medicinally active chelates were prepared from Cu (II), VO (II), Ag (I) and Pd (II) ions
with N-(1H-Benzoimidazol-2-yl)-guanidine, BIG ligand. The ligand performed as bi-dentate …

Synthesis of new Cu (II)-benzohydrazide nanometer complexes, spectral, modeling, CT-DNA binding with potential anti-inflammatory and anti-allergic theoretical …

HA Katouah, JH Al-Fahemi, MG Elghalban… - Materials Science and …, 2019 - Elsevier
New nanometer Cu (II)-benzohydrazide complexes were synthesized and characterized.
Mono negative tetra-dentate mode is the general feature proposed for all coordinating …

Development of New Mixed Cu (II) Chelate Based on 2-Benzimidazolylguanidine and Phenanthroline Ligands: Structural Elucidation, Biological Evaluation, DFT and …

AM Abu-Dief, T El-dabea, RM El-Khatib… - Sohag Journal of …, 2024 - sjsci.journals.ekb.eg
A new mixed ligand complex with metal ion Cu (II) of the type [Cu (II): HL: P](where HL= 2-
Benzimidazolylguanidine and P= Phenanthroline) was synthesized and characterized using …

Structural inspection for novel Pd (II), VO (II), Zn (II) and Cr (III)-azomethine metal chelates: DNA interaction, biological screening and theoretical treatments

FS Aljohani, AM Abu-Dief, RM El-Khatib… - Journal of Molecular …, 2021 - Elsevier
An alternative sequence of bioactive series, using novel Schiff base derivative (1-Quinolin-8-
yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar …

Synthesis, DFT calculation, DNA-binding, antimicrobial, cytotoxic and molecular docking studies on new complexes VO (II), Fe (III), Co (II), Ni (II) and Cu (II) of pyridine …

NO AlZamil - Materials Research Express, 2020 - iopscience.iop.org
Abstract A new H 2 L ligand (6, 6'-(pyridine-2, 6-diylbis (azan-1-yl-1-ylidene)) bis (methan-1-
yl-1-ylidene) bis (2-ethoxyphenol) was obtained from the reaction of 2, 6-diamino pyridine …

DNA/protein binding, DNA cleavage, cytotoxicity, superoxide radical scavenging and molecular docking studies of copper (II) complexes containing N-benzyl-N′-aryl …

K Jeyalakshmi, Y Arun, NSP Bhuvanesh… - Inorganic Chemistry …, 2015 - pubs.rsc.org
Five copper (II) complexes containing N, N′, N′′-trisubstituted guanidine ligands were
synthesized and characterized by elemental analyses and UV-Visible, FT-IR, EPR and mass …

Synthesis, structural characterization, DFT calculations, biological investigation, molecular docking and DNA binding of Co (II), Ni (II) and Cu (II) nanosized Schiff base …

MT Basha, RM Alghanmi, MR Shehata… - Journal of Molecular …, 2019 - Elsevier
Three new NNO tridentate Schiff bases derived from 5-bromosalicylaldehyde with 2-amino-
4, 6-dimethylpyrimidine, 2-amino-4-methoxy-6-methylpyrimidine and 2-amino-4-chloro-6 …