Quantifying variabilities in cardiac digital twin models of the electrocardiogram

E Zappon, MAF Gsell, K Gillette, G Plank - arXiv preprint arXiv:2407.17146, 2024 - arxiv.org
CDT of human cardiac EP are digital replicas of patient hearts that match like-for-like clinical
observations. The ECG, as the most prevalent non-invasive observation of cardiac …

[HTML][HTML] A framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs

K Gillette, MAF Gsell, AJ Prassl, E Karabelas… - Medical image …, 2021 - Elsevier
Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

Personalized Topology-Informed 12-Lead ECG Electrode Localization from Incomplete Cardiac MRIs for Efficient Cardiac Digital Twins

L Li, H Smith, Y Lyu, J Camps, B Rodriguez… - arXiv preprint arXiv …, 2024 - arxiv.org
Cardiac digital twins (CDTs) offer personalized\textit {in-silico} cardiac representations for
the inference of multi-scale properties tied to cardiac mechanisms. The creation of CDTs …

pyCEPS: A cross-platform Electroanatomic Mapping Data to Computational Model Conversion Platform for the Calibration of Digital Twin Models of Cardiac …

R Arnold, AJ Prassl, A Neic, F Thaler… - arXiv preprint arXiv …, 2024 - arxiv.org
Background and Objective: Data from electro-anatomical mapping (EAM) systems are
playing an increasingly important role in computational modeling studies for the patient …

Cardiac digital twins of the adult population: linking electrophysiological functions to anatomy

S Qian, D Ugurlu, E Fairweather, M Strocchi… - Europace, 2023 - academic.oup.com
Abstract Funding Acknowledgements Type of funding sources: Public grant (s)–National
budget only. Main funding source (s): This project is supported by the Wellcome Trust and …

Solving the Inverse Problem of Electrocardiography for Cardiac Digital Twins: A Survey

L Li, J Camps, B Rodriguez, V Grau - arXiv preprint arXiv:2406.11445, 2024 - arxiv.org
Cardiac digital twins are personalized virtual representations used to understand complex
heart mechanisms. Solving the ECG inverse problem is crucial for accurate virtual heart …

Towards enabling cardiac digital twins of myocardial infarction using deep computational models for inverse inference

L Li, J Camps, Z Wang, M Beetz… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Cardiac digital twins (CDTs) have the potential to offer individualized evaluation of cardiac
function in a non-invasive manner, making them a promising approach for personalized …

Digital twinning of cardiac electrophysiology models from the surface ECG: a geodesic backpropagation approach

T Grandits, J Verhülsdonk, G Haase… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
The eikonal equation has become an indispensable tool for modeling cardiac electrical
activation accurately and efficiently. In principle, by matching clinically recorded and eikonal …

Towards the development of virtual heart technology for creating digital twins of cardiac electrophysiology

MAF Gsell, L Azzolin, KK Gillette, A Neic… - 2023 Computing in …, 2023 - ieeexplore.ieee.org
Introduction: Virtual heart technologies (VHTs) promise to offer an detailed view on cardiac
electrophysiology (EP). However, only very few VHTs simulating EP of four-chamber hearts …

Deep computational model for the inference of ventricular activation properties

L Li, J Camps, A Banerjee, M Beetz… - … Workshop on Statistical …, 2022 - Springer
Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …