Bispecific antibody pretargeting is highly sensitive and specific for cancer detection by PET.
In this study, the preparation of a high-specific-activity 68Ga-labeled hapten-peptide …

We previously described a highly flexible bispecific antibody (bs-mAb) pretargeting
procedure using a multivalent, recombinant anti-CEA (carcinoembryonic antigen)× anti-HSG …

The aim of this work was to develop reagents and methods potentially useful in PET, using
68Ga in a 2-step pretargeting protocol. Methods: We prepared bispecific antibodies (bsAbs) …

Background Pretargeted immuno-PET tumor imaging has emerged as a valuable diagnostic
strategy that combines the high specificity of antibody-antigen interaction with the high …

Abstract 18 F-Fluorodeoxyglucose (18 F-FDG) is the most common molecular imaging agent
in oncology, with a high sensitivity and specificity for detecting a number of cancers …

Purpose Pretargeting with bispecific antibodies and radiolabeled hapten-peptides could be
used to specifically target tumors with high target-to-background ratios. TF12 is a trivalent …

Abstract Purpose Monoclonal antibodies (MAbs) labelled with 124 I are an attractive option
for quantitative imaging with positron emission tomography (PET) in a scouting procedure …

Labeled antibodies, as well as their fragments and antibody-derived recombinant constructs,
have long been proposed as general vectors to target radionuclides to tumor lesions for …

Immuno-PET as a scouting procedure before radioimmunotherapy (RIT) aims at the
confirmation of tumor targeting and the accurate estimation of radiation dose delivery to both …

Purpose The aim of this study was to compare the performances pretargeted immunoPET 68
Ga-PETimaging (68 Ga-pPET) with anti carcino-embryonic antigen (CEA) and anti …