Given the strong trend to implement zebrafish (Danio rerio) embryos as translational model
not only in ecotoxicological, but also toxicological testing strategies, there is an increasing …

The zebrafish (Danio rerio) has been increasingly explored in pharmaceutical research as a
promising alternative model for toxicological screens. This necessitates a thorough …

Zebrafish embryos are being increasingly used as model organisms for the assessment of
single substances and complex environmental samples for regulatory purposes. Thus, it is …

Increasing use of zebrafish in biomedical, toxicological and developmental studies requires
explicit knowledge of cytochrome P450 (CYP), given the central role of CYP in oxidative …

Endpoints of planar halogenated aromatic hydrocarbon (pHAH) and polycyclic aromatic
hydrocarbon (PAH) toxicity are mediated via activation of the aryl hydrocarbon receptor …

Zebrafish are used widely in biomedical, toxicological, and developmental research, but
information on their xenobiotic metabolism is limited. Here, we characterized the expression …

The zebrafish (Danio rerio) is increasingly used as a screening model for acute, chronic and
developmental toxicity. More specifically, the embryo is currently investigated as a …

Background Increasing use of zebrafish in drug discovery and mechanistic toxicology
demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP …

At present, the zebrafish embryo is increasingly used as an alternative animal model to
screen for developmental toxicity after exposure to xenobiotics. Since zebrafish embryos …

The zebrafish (Danio rerio) embryo is currently explored as an alternative for developmental
toxicity testing. As maternal metabolism is lacking in this model, knowledge of the disposition …