Conditions within the tumor microenvironment, including cytokines and low oxygen levels,
affect the interaction of host immune cells with tumor. The effect of these factors was studied …

Carcinomas are composed of neoplastic epithelial cells, which form the heart of the tumor,
as well as a variety of mesenchymal cell types and extracellular matrix components that …

This volume discusses recent research advances in cancer biology, focusing on the role of
the tumor microenvironment. Taken alongside its companion volumes, Tumor …

“The road to metastasis is paved with tumor-microenvironment interactions”, claimed Dr.
Isaac Witz from Tel Aviv University, Israel, in his keynote speech at the first Tianjin Forum on …

The interactions between cells in their native microenvironment are critical to understanding
the mechanisms regulating diverse aspects of biological processes in both healthy and …

Tumor microenvironment is formed by various cellular and non-cellular components which
interact with one another and form a complex network of interactions. Some of these cellular …

Our understanding of tumor biology has evolved from the consideration of only tumor cell
autonomous changes to the realization of the plethora of interactions among various cells …

Tumors are complex cellular and acellular environments within which cancer clones are
under continuous selection pressures. Cancer cells are in a permanent mode of interaction …

Purpose The role of the microenvironment during the initiation and progression of
carcinogenesis is now realized to be of critical importance, both for enhanced understanding …

The interactions between cancer cells and their micro-and macroenvironment create a
context that promotes tumour growth and protects it from immune attack. The functional …