Background Male sex reversal syndrome is a rare genetic cause of male infertility with an
overall incidence of 1/20,000–1/100,000 males. There is mismatching between the genetic …

Summary 46, XX male sex reversal syndrome is one of the rarest sex chromosomal
aberrations. The presence of SRY gene on one of the X chromosomes is the most frequent …

Purpose: To identify the clinical characteristics of SRY-negative male patients and genes
related to male sex reversal, we performed a retrospective study using cases of 46, XX …

Purpose To investigate the clinical characteristics of different categories of sex-reversed 46,
XX individuals and their relationships with chromosomal karyotype and the SRY gene …

Sex reversal syndrome is a kind of human genetic disease about gender dysplasia, which is
characterised by inconsistency between gonadal sexuality and chromosome sexuality; the …

The sex-determining region on the Y chromosome (SRY) gene guides male sexual
development. However, individuals with sex reversal syndrome (46, XX males and 46, XX …

Southern blot hybridization using Y-specific DNA probes and electrophoretic analysis of the
SRY gene fragment amplified through polymerase chain reaction (PCR) have been …

Abstract 46, XX male sex reversal syndrome is a rare genetic cause of male infertility. We
report on two new cases of this syndrome in men presenting with hypogonadism and …

Background To review the possible mechanisms proposed to explain the etiology of 46, XX
sex reversal by investigating the clinical characteristics and their relationships with …

Sex reversal in the presence of a 46, XY karyotype can result from mutations of the testis-
determining gene SRY (“sex-determining region Y”), the protein product of which is an …