Vitamin B2‐based ferroptosis promoter for sono‐enhanced nanocatalytic therapy of triple‐negative breast cancer
M Zhou, M Yuan, Y Jin, Q Zhou, Y Yu… - Advanced Functional …, 2023 - Wiley Online Library
Ferroptosis featured by iron‐dependent lipid peroxidation plays a critical role in tumor
regression, offering an alternative therapeutic target for the treatment of aggressive triple …
regression, offering an alternative therapeutic target for the treatment of aggressive triple …
[HTML][HTML] MR imaging guided iron-based nanoenzyme for synergistic Ferroptosis− Starvation therapy in triple negative breast cancer
D Wang, W Fang, C Huang, Z Chen, T Nie… - Smart Materials in …, 2022 - Elsevier
Triple negative breast cancer (TNBC), as the most aggressive BC, accounts for the leading
cause of worldwide women death. Owing to the deficiency of related hormone receptors, the …
cause of worldwide women death. Owing to the deficiency of related hormone receptors, the …
Synergistic functional nanomedicine enhances ferroptosis therapy for breast tumors by a blocking defensive redox system
S Chen, J Yang, Z Liang, Z Li, W Xiong… - … Applied Materials & …, 2023 - ACS Publications
The upregulation of dihydroorotate dehydrogenase (DHODH) redox systems inside tumor
cells provides a powerful shelter against lipid peroxidation (LPO), impeding ferroptosis …
cells provides a powerful shelter against lipid peroxidation (LPO), impeding ferroptosis …
Metal-rich cascade nanosystem for dual-pathway ferroptosis resistance regulation and photothermal effect for efficient tumor combination therapy
X Liu, P Guan, J Mu, Z Meng, H Lian - Biomaterials Science, 2023 - pubs.rsc.org
Despite the therapeutic response of ferroptosis in various tumors, ferroptosis resistance has
been found in numerous studies, significantly hindering the progress of ferroptosis anti …
been found in numerous studies, significantly hindering the progress of ferroptosis anti …
A MOF-based potent ferroptosis inducer for enhanced radiotherapy of triple negative breast cancer
L Zeng, S Ding, Y Cao, C Li, B Zhao, Z Ma, J Zhou… - ACS …, 2023 - ACS Publications
Radiotherapy (RT) is one of the important clinical treatments for local control of triple-
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …
A bimetallic dual-targeting nanoplatform for combinational ferroptosis activation/epigenetic regulation/photothermal therapy against breast cancer and tumor …
Z He, H Zhou, Q Feng, Y Zhang, S Gao, S Liu… - Chemical Engineering …, 2024 - Elsevier
Restricted by the complex intracellular ferroptosis regulatory networks, single ferroptotic
therapy against breast cancer (BC) yields limited therapeutic outcomes. Therefore, novel …
therapy against breast cancer (BC) yields limited therapeutic outcomes. Therefore, novel …
Simvastatin induced ferroptosis for triple-negative breast cancer therapy
X Yao, R Xie, Y Cao, J Tang, Y Men, H Peng… - Journal of …, 2021 - Springer
Triple-negative breast cancer (TNBC), a management of aggressive breast cancer, remains
an unmet medical challenge. Although a wave of efforts had spurred to design novel …
an unmet medical challenge. Although a wave of efforts had spurred to design novel …
Multienzyme-like reactivity cooperatively impairs glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways in triple-negative breast cancer for sensitized …
Ferroptosis is a recently discovered route of regulated cell death that offers the opportunities
for the treatment of chemotherapy-resistant tumor indications, but its efficacy can be affected …
for the treatment of chemotherapy-resistant tumor indications, but its efficacy can be affected …
Tumor Microenvironment‐Activatable Metal‐Phenolic Nanoformulations for Ultrasound‐Boosted Ferroptosis through Triple Regulatory Pathways
Z Liu, S Liu, B Liu, Q Meng, M Yuan… - Advanced Functional …, 2024 - Wiley Online Library
Despite its effectiveness in exterminating tumor cells, ferroptosis is seriously hampered by
the high expression of antioxidant glutathione (GSH) and the inadequacy of endogenous …
the high expression of antioxidant glutathione (GSH) and the inadequacy of endogenous …
Nanomedicine-mediated ferroptosis targeting strategies for synergistic cancer therapy
W Yin, J Chang, J Sun, T Zhang, Y Zhao, Y Li… - Journal of Materials …, 2023 - pubs.rsc.org
Apoptosis-based treatment plays an important role in regulating the death of tumor cells (eg,
chemotherapy, radiotherapy, and immunotherapy). Nevertheless, cancer cells can escape …
chemotherapy, radiotherapy, and immunotherapy). Nevertheless, cancer cells can escape …
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