A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection
P Wang, R Luo, M Zhang, Y Wang, T Song, T Tao… - Cell death & …, 2020 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is an acute and rapidly developing pandemic,
which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and …
which leads to a global health crisis. SARS-CoV-2 primarily attacks human alveoli and …
Biomimetic human disease model of SARS‐CoV‐2‐induced lung injury and immune responses on organ chip system
M Zhang, P Wang, R Luo, Y Wang, Z Li… - Advanced …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a global pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The models that can accurately …
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The models that can accurately …
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19
F D'Agnillo, KA Walters, Y Xiao, ZM Sheng… - Science translational …, 2021 - science.org
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is characterized by respiratory distress, multiorgan …
coronavirus 2 (SARS-CoV-2), is characterized by respiratory distress, multiorgan …
SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction
S Deinhardt-Emmer, S Böttcher, C Häring… - Journal of …, 2021 - Am Soc Microbiol
Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be
asymptomatic, but they can also be accompanied by a variety of symptoms that result in mild …
asymptomatic, but they can also be accompanied by a variety of symptoms that result in mild …
SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro
SARS-CoV-2 infection can cause fatal inflammatory lung pathology, including thrombosis
and increased pulmonary vascular permeability leading to edema and hemorrhage. In …
and increased pulmonary vascular permeability leading to edema and hemorrhage. In …
Single-cell analysis reveals bronchoalveolar epithelial dysfunction in COVID-19 patients
In 2019, a zoonotic coronavirus named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was identified as the causative agent of Coronavirus Disease 2019 (COVID …
(SARS-CoV-2) was identified as the causative agent of Coronavirus Disease 2019 (COVID …
[HTML][HTML] Endothelial cell infection and dysfunction, immune activation in severe COVID-19
Rationale: Pulmonary vascular endotheliitis, perivascular inflammation, and immune
activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly …
activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly …
The enigma of endothelium in COVID-19
S Kaur, DM Tripathi, A Yadav - Frontiers in Physiology, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome–
related coronavirus-2 (SARS-CoV-2) has affected millions of people globally. Clinically, it …
related coronavirus-2 (SARS-CoV-2) has affected millions of people globally. Clinically, it …
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes
There are currently limited Food and Drug Administration (FDA)-approved drugs and
vaccines for the treatment or prevention of Coronavirus Disease 2019 (COVID-19) …
vaccines for the treatment or prevention of Coronavirus Disease 2019 (COVID-19) …
SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients
Abstract Background The outbreak of Coronavirus disease 2019 (COVID-19) caused by
SARS-CoV-2 infection has become a global health emergency. We aim to decipher SARS …
SARS-CoV-2 infection has become a global health emergency. We aim to decipher SARS …
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