A diselenium-bridged covalent organic framework with pH/GSH/photo-triple-responsiveness for highly controlled drug release toward joint chemo/photothermal …

H Lou, L Chu, W Zhou, J Dou, X Teng, W Tan… - Journal of Materials …, 2022 - pubs.rsc.org
Here, a novel joint chemo/photothermal/chemodynamic therapy was developed using a
pH/GSH/photo triple-responsive 2D-covalent organic framework (COF) drug carriers for …

Copper sulfide engineered covalent organic frameworks for pH-responsive chemo/photothermal/chemodynamic synergistic therapy against cancer

S Wang, Y Pang, S Hu, J Lv, Y Lin, M Li - Chemical Engineering Journal, 2023 - Elsevier
Developing nanomedicines with high-performance is a promising therapeutic strategy for
cancer treatment. Herein, a multifunctional nanoplatform (CuS@ COFs-BSA-FA/DOX) based …

Covalent organic framework-engineered polydopamine nanoplatform for multimodal imaging-guided tumor photothermal-chemotherapy

P Gao, R Wei, X Liu, Y Chen, T Wu, M Shi… - Chemical …, 2021 - pubs.rsc.org
A covalent organic framework (COF)-engineered polydopamine core–shell nanoplatform
(PDA@ COF) was developed. The ultrasmall pores and abundant functional sites of the COF …

Mitochondria-targeting and ROS-sensitive smart nanoscale supramolecular organic framework for combinational amplified photodynamic therapy and chemotherapy

J Tian, B Huang, Z Cui, P Wang, S Chen, G Yang… - Acta Biomaterialia, 2021 - Elsevier
Owing to their reversibly dynamic features, and the regularity of their architectures,
supramolecular organic frameworks (SOFs) have attracted attention as new porous …

A biodegradable covalent organic framework for synergistic tumor therapy

WY Li, JJ Wan, JL Kan, B Wang, T Song, Q Guan… - Chemical …, 2023 - pubs.rsc.org
Stimulus-responsive biodegradable nanocarriers with tumor-selective targeted drug delivery
are critical for cancer therapy. Herein, we report for the first time a redox-responsive disulfide …

Nanoscale covalent organic framework for combinatorial antitumor photodynamic and photothermal therapy

Q Guan, LL Zhou, YA Li, WY Li, S Wang, C Song… - ACS …, 2019 - ACS Publications
Despite the excellent photodynamic and photothermal properties of organic molecular
photosensitizers (PSs) and photothermal agents (PTAs), such as porphyrin and …

Light-activated hypoxia-sensitive covalent organic framework for tandem-responsive drug delivery

L Ge, C Qiao, Y Tang, X Zhang, X Jiang - Nano Letters, 2021 - ACS Publications
Covalent organic frameworks (COFs) have received much attention in the biomedical area.
However, little has been reported about stimuli-responsive COF for drug delivery. Herein, we …

Polydopamine-Modified Zeolite Imidazole Framework Drug Delivery System for Photothermal Chemotherapy of Hepatocellular Carcinoma

Q Hu, L Xu, X Huang, Y Duan, D Sun, Z Fu… - …, 2023 - ACS Publications
Metal–organic frameworks (MOFs) are promising drug-delivering platforms for their intrinsic
capability of loading and releasing different cargoes. To further extend their biomedical …

A reactive oxygen species-responsive covalent organic framework for tumor combination therapy

WY Li, JL Kan, JJ Wan, YA Li, T Song… - Chemical …, 2023 - pubs.rsc.org
Herein, we report the first reactive oxygen species (ROS)-responsive dithioketal-linked
covalent organic framework (COF) for synergetic chemotherapy and photodynamic therapy …

Programmable therapeutic nanoscale covalent organic framework for photodynamic therapy and hypoxia-activated cascade chemotherapy

H He, L Du, H Xue, J Wu, X Shuai - Acta Biomaterialia, 2022 - Elsevier
Clinical photodynamic therapy (PDT) only has a limited cancer therapeutic effect and
typically leads to a more hypoxic milieu owing to the hypoxic conditions of the solid tumor …