Toxicology and pharmacology of synthetic organoselenium compounds: An update
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …
compounds and some naturally occurring organoselenium amino acids. The use of …
Organoselenium compounds as potential therapeutic and chemopreventive agents: a review
M Soriano-Garcia - Current medicinal chemistry, 2004 - ingentaconnect.com
Selenium is an essential trace element. It is, however toxic at concentration little above
which is required for health. Selenium is incorporated into proteins as selenocysteine, the …
which is required for health. Selenium is incorporated into proteins as selenocysteine, the …
Organoselenium compounds as mimics of selenoproteins and thiol modifier agents
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …
Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds
CW Nogueira, JBT Rocha - Archives of Toxicology, 2011 - Springer
The advance in the area of synthesis and reactivity of organoselenium, as well as the
discovery that selenium was the cause of severe intoxication episodes of livestock in the …
discovery that selenium was the cause of severe intoxication episodes of livestock in the …
Selenium as an emerging versatile player in heterocycles and natural products modification
W Hou, H Dong, X Zhang, Y Wang, L Su, H Xu - Drug Discovery Today, 2022 - Elsevier
The diverse pharmacological activities of organoselenium compounds are closely correlated
to their ability to scavenge and induce reactive oxygen species (ROS), their intrinsic …
to their ability to scavenge and induce reactive oxygen species (ROS), their intrinsic …
Selenium-based antihypertensives: rationale and potential
SW May, SH Pollock - Drugs, 1998 - Springer
Selenium, long recognised as an important 'dietary antioxidant', is now known to be an
essential component of the active sites of a number of enzymes, including the glutathione …
essential component of the active sites of a number of enzymes, including the glutathione …
Organoselenium compounds: Chemistry and applications in organic synthesis
JM Sonego, SI De Diego, SH Szajnman… - … A European Journal, 2023 - Wiley Online Library
Selenium, originally described as a toxin, turns out to be a crucial trace element for life that
appears as selenocysteine and its dimer, selenocystine. From the point of view of drug …
appears as selenocysteine and its dimer, selenocystine. From the point of view of drug …
Recent advances in the synthesis and antioxidant activity of low molecular mass organoselenium molecules
JM Anghinoni, PT Birmann, MJ da Rocha, CS Gomes… - Molecules, 2023 - mdpi.com
Selenium is an essential trace element in living organisms, and is present in selenoenzymes
with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) …
with antioxidant activity, like glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) …
Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: the selenium paradox
KH Lee, D Jeong - Molecular medicine reports, 2012 - spandidos-publications.com
Selenium is an essential biological trace element. Adult daily intake of selenium should be
approximately 100 µg per day. This compound has a two-sided effect depending on its …
approximately 100 µg per day. This compound has a two-sided effect depending on its …
[图书][B] Organoselenium compounds in biology and medicine: synthesis, biological and therapeutic treatments
VK Jain, KI Priyadarsini - 2017 - books.google.com
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This
book discusses organoselenium chemistry and biology in the context of its therapeutic …
book discusses organoselenium chemistry and biology in the context of its therapeutic …