Frailty, a consequence of the interaction of the aging process and certain chronic diseases,
compromises functional outcomes in the elderly and substantially increases their risk for …

Sarcopenia is a major component of the frailty syndrome, both being considered as strong
predictors of morbidity, disability, and death in older people. In this review, we explore the …

Longitudinal studies demonstrate that regular physical exercise extends longevity and
reduces the risk of physical disability. Decline in physical activity with aging is associated …

The population is ageing worldwide at a phenomenal pace from 900 million≥ 60 years old
in 2015 to 2 billion in 2050 (1). The longer lifespan is due to advancement in public health …

Frailty is a common condition in older persons and has been described as a geriatric
syndrome resulting from age-related cumulative declines across multiple physiologic …

Oxidative stress plays a key role in the aging process. Lifestyle behaviours including low
physical activity and inadequate nutritional habits in addition to genetic susceptibility and …

The frailty syndrome is increasingly recognized by geriatricians to identify elders at an
extreme risk of adverse health outcomes. The physiological changes that result in frailty are …

Frailty is a clinical geriatric syndrome caused by physiological deficits across multiple
systems. These deficits make it challenging to sustain homeostasis required for the …

Frailty has emerged as a true geriatric syndrome with increasing interest for both basic
scientist as well as clinicians. The conceptual frame of a decreased resistance to internal …

The identification of cost-effective interventions that improve the health status and prevent
disability in old age is one of the most important public health challenges. Regular physical …