Comprehensive molecular motion capture for sphingomyelin by site-specific deuterium labeling

N Matsumori, T Yasuda, H Okazaki, T Suzuki… - Biochemistry, 2012 - ACS Publications
Lipid rafts have attracted much attention because of their significant functional roles in
membrane-associated processes. It is thought that sphingomyelin and cholesterol are …

Detailed comparison of deuterium quadrupole profiles between sphingomyelin and phosphatidylcholine bilayers

T Yasuda, M Kinoshita, M Murata, N Matsumori - Biophysical Journal, 2014 - cell.com
Lipid rafts are microdomains rich in sphingomyelin (SM) and cholesterol (Chol). The
essential question is why natural lipid rafts prefer SM rather than saturated diacyl …

Orientation and order of the amide group of sphingomyelin in bilayers determined by solid-state NMR

N Matsumori, T Yamaguchi, Y Maeta, M Murata - Biophysical Journal, 2015 - cell.com
Sphingomyelin (SM) and cholesterol (Chol) are considered essential for the formation of
lipid rafts; however, the types of molecular interactions involved in this process, such as …

Cholesterol-induced conformational change in the sphingomyelin headgroup

S Hanashima, K Murakami, M Yura, Y Yano… - Biophysical …, 2019 - cell.com
Sphingomyelin (SM) and cholesterol (Cho) are the important lipids for the formation of
biologically functional membrane domains, lipid rafts. However, the interaction between Cho …

[HTML][HTML] Structure and dynamics of sphingomyelin bilayer: insight gained through systematic comparison to phosphatidylcholine

P Niemelä, MT Hyvönen, I Vattulainen - Biophysical journal, 2004 - cell.com
Sphingomyelin, one of the main lipid components of biological membranes, is actively
involved in various cellular processes such as protein trafficking and signal transduction. In …

Evidence of lipid rafts based on the partition and dynamic behavior of sphingomyelins

M Kinoshita, KGN Suzuki, M Murata… - Chemistry and physics of …, 2018 - Elsevier
Sphingomyelin (SM)-rich membrane nano-domains, called lipid rafts, have attracted the
interest of researchers due to their potential involvement in the formation of signaling …

[HTML][HTML] Hydrogen-bonding propensities of sphingomyelin in solution and in a bilayer assembly: a molecular dynamics study

E Mombelli, R Morris, W Taylor, F Fraternali - Biophysical Journal, 2003 - cell.com
Sphingomyelin is enriched within lipid microdomains of the cell membrane termed lipid rafts.
These microdomains play a part in regulating a variety of cellular events. Computer …

Deuterium NMR of raft model membranes reveals domain-specific order profiles and compositional distribution

T Yasuda, H Tsuchikawa, M Murata, N Matsumori - Biophysical Journal, 2015 - cell.com
In this report, we applied site-specifically deuterated N-stearoylsphingomyelins (SSMs) to
raft-exhibiting ternary mixtures containing SSM, 1, 2-dioleoyl-sn-glycero-3-phosphocholine …

Raft-based sphingomyelin interactions revealed by new fluorescent sphingomyelin analogs

M Kinoshita, KGN Suzuki, N Matsumori… - Journal of Cell …, 2017 - rupress.org
Sphingomyelin (SM) has been proposed to form cholesterol-dependent raft domains and
sphingolipid domains in the plasma membrane (PM). How SM contributes to the formation …

Effect of sphingomyelin headgroup size on molecular properties and interactions with cholesterol

A Björkbom, T Róg, K Kaszuba, M Kurita… - Biophysical journal, 2010 - cell.com
Sphingomyelins (SMs) and sterols are important constituents of the plasma membrane and
have also been identified as major lipid components in membrane rafts. Using SM analogs …