Anti-mitochondrial antibody titers decrease over time in primary biliary cholangitis patients with ursodeoxycholic acid therapeutic response: a cohort study followed up …

ML Chang, WT Chen, TM Chan, CY Lin… - Frontiers in …, 2022 - frontiersin.org
Background How anti-mitochondrial antibody (AMA) and liver biochemistry levels change in
primary biliary cholangitis (PBC) patients treated with ursodeoxycholic acid (UDCA) remains …

Evidence for the association between IgG‐antimitochondrial antibody and biochemical response to ursodeoxycholic acid treatment in primary biliary cholangitis

L Tang, R Zhong, X He, W Wang, J Liu… - Journal of …, 2017 - Wiley Online Library
Abstract Background and Aim Antimitochondrial antibody (AMA) is considered the
serological hallmark of primary biliary cholangitis (PBC), while data regarding the profile of …

Does antimitochondrial antibody status affect response to treatment in patients with primary biliary cirrhosis? Outcomes of ursodeoxycholic acid therapy and liver …

WR Kim, JJ Poterucha, RA Jorgensen, KP Batts… - Hepatology, 1997 - journals.lww.com
Abstract Approximately 5% to 10% of patients with features otherwise consistent with
primary biliary cirrhosis (PBC) lack antimitochondrial antibodies (AMA). Most of these …

Anti-mitochondrial antibody-negative primary biliary cholangitis is part of the same spectrum of classical primary biliary cholangitis

GGL Cançado, MH Braga, MLG Ferraz… - Digestive diseases and …, 2021 - Springer
Background Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease in which
anti-mitochondrial antibodies (AMA) are the diagnostic hallmark. Whether AMA-negative …

Low rate of new‐onset primary biliary cholangitis in a cohort of anti‐mitochondrial antibody‐positive subjects over six years of follow‐up

S Zandanell, M Strasser, A Feldman… - Journal of Internal …, 2020 - Wiley Online Library
Abstract Background and Aims Anti‐mitochondrial antibodies (AMA) are closely linked to
primary biliary cholangitis (PBC). The prevalence of AMA in the general population is low …

Rates of decompensation, hepatocellular carcinoma and mortality in AMA‐negative primary biliary cholangitis cirrhosis

BV John, B Dahman, Y Deng, NS Khakoo… - Liver …, 2022 - Wiley Online Library
Background The natural history of patients with anti‐mitochondrial antibody (AMA)‐negative
Primary Biliary Cholangitis (PBC) cirrhosis has not been well defined, with prior studies …

Clinical significance of IgG antimitochondrial M2 antibody levels in primary biliary cholangitis: A single center study from China

L Feng, K Dong, X Zhang, B Ma, L Chen, Q Yang… - Plos one, 2020 - journals.plos.org
Background and objective The relationship between antimitochondrial antibody (AMA)
levels and the severity or prognosis of primary biliary cholangitis (PBC) is unclear. This study …

The challenges of primary biliary cholangitis: What is new and what needs to be done

BT Beretta-Piccoli, G Mieli-Vergani, D Vergani… - Journal of …, 2019 - Elsevier
Abstract Primary Biliary Cholangitis (PBC) is an uncommon, chronic, cholangiopathy of
autoimmune origin and unknown etiology characterized by positive anti-mitochondrial …

Evolutionary relationship between antimitochondrial antibody positivity and primary biliary cholangitis in Taiwan: a 16-year hospital cohort study

ML Chang, JS Cheng, PH Le… - Therapeutic …, 2024 - journals.sagepub.com
Background: How antimitochondrial antibody (AMA)-positive patients evolve to have primary
biliary cholangitis (PBC) in viral hepatitis–endemic areas is unknown. Objectives: We aimed …

[PDF][PDF] The future risk of primary biliary cholangitis (PBC) is low among patients with incidental anti‐mitochondrial antibodies but without baseline PBC

W Duan, S Chen, S Li, T Lv, B Li… - Hepatology …, 2022 - Wiley Online Library
Anti‐mitochondrial autoantibodies (AMAs) are highly specific for the diagnosis of primary
biliary cholangitis (PBC) but are also occasionally found in other diseases. In the present …