Cells interact with their surrounding environment through a combination of static and
dynamic mechanical signals that vary over stimulus types, intensity, space, and time …

Synthetic hydrogels have ideal physiochemical properties to serve as reductionist mimics of
the extracellular matrix (ECM) for studies on cellular mechanosensing. These studies range …

Advancements in materials-driven mechanobiology have yielded significant progress.
Mechanobiology explores how cellular and tissue mechanics impact development …

The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

Human tissues are sophisticated ensembles of various distinct cell types encapsulated in
the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a …

Biophysical cues can potently direct a cell's or tissue's behavior. Cells interpret their
biophysical surroundings, such as matrix stiffness or dynamic mechanical stimulation …

The development of hydrogel-based biomaterials represents a promising approach to
generating new strategies for tissue engineering and regenerative medicine. In order to …

Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

Stem cells hold great promise for widespread biomedical applications, for which stem cell
fate needs to be well tailored. Besides biochemical cues, accumulating evidence has …