Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis,
there are selective C or Aδ epidermal nerve endings that are pruriceptors. At their other …

For centuries, itch was categorized as a submodality of pain. Recent research over the last
decade has led to the realization that itch is in fact a separate and distinct, albeit closely …

Chronic itch represents a burdensome clinical problem that can originate from a variety of
aetiologies. Pruriceptive itch originates following the activation of peripheral sensory nerve …

Chronic pruritus has multiple etiologies, ranging from inflammatory to metabolic and
neuropathic processes. However, recent advances in itch biology have shed light on …

Itch, also known as pruritus, is the major symptom in skin diseases with a variety of
etiologies and pathophysiologies. Significant progress has been achieved in understanding …

Itch (or pruritus) is an unpleasant sensation inducing a desire to scratch. As part of the
body's defense mechanism, itch guards the skin against potentially dangerous organisms or …

To cite this article: Buddenkotte J, Steinhoff M. Pathophysiology and therapy of pruritus in
allergic and atopic diseases. Allergy 2010; 65: 805–821. Abstract Pruritus (itch) is a major …

Pruritus, regularly defined as an unpleasant sensation provoking the desire to scratch (1), is
an essential feature of atopic dermatitis (AD)(2, 3). Because of the high impact on life quality …

Itch is a common sensory experience that is prevalent in patients with inflammatory skin
diseases, as well as in those with systemic and neuropathic conditions. In patients with …

Classification of itch into four categories—pruritoceptive, neurogenic, neuropathic, and
psychogenic—has proven to be of utility to clinicians and investigators. Itch is recognized to …