Opioid addiction is associated with excess mortality, morbidities, and other adverse
conditions. Guided by a life-course framework, we review the literature on the long-term …

Illicit use of opiates is the fastest growing substance use problem in the United States, and
the main reason for seeking addiction treatment services for illicit drug use throughout the …

The development of effective treatments for opioid dependence is of great importance given
the devastating consequences of the disease. Pharmacotherapies for opioid addiction …

Learning Objective: After participating in this activity, learners should be better able to:
Evaluate the rationale for and current evidence supporting medication-assisted treatment of …

While opioid dependence has more treatment agents available than other abused drugs,
none are curative. They can, however, markedly diminish withdrawal symptoms and craving …

BACKGROUND: Prescription opioid dependence is a growing problem, but little research
exists on its treatment, including patient characteristics that predict treatment outcome …

Opioid use disorder (OUD) is a chronic, relapsing condition, often associated with legal,
interpersonal, and employment problems. Medications demonstrated to be effective for OUD …

Objective: To provide an overview of treatment options for opioid-dependent patients.
Method: We screened all published studies on the treatment of opioid dependence, with a …

Opioid dependence, manifesting as addiction to heroin and pharmaceutical opioids is
increasing. Internationally, there are an estimated 15.6 million illicit opioid users. The global …

Aims. To evaluate the safety and efficacy of an 8 mg/day sublingual dose of buprenorphine
in the maintenance treatment of heroin addicts by comparison with a 1 mg/day dose over a …