The regulation of transcription by RNA polymerase II is closely intertwined with the
regulation of chromatin structure. A host of proteins required for the disassembly …

The conserved, multifunctional Polymerase-Associated Factor 1 complex (Paf1C) regulates
all stages of the RNA polymerase (Pol) II transcription cycle. In this review, we examine a …

Pleiotropic transcription regulator RNA polymerase II (Pol II)–associated factor 1 (PAF1)
governs multiple transcriptional steps and the deposition of several epigenetic marks …

RNA polymerase II (Pol2) movement through chromatin and the co-transcriptional
processing and fate of nascent transcripts is coordinated by transcription elongation factors …

The Paf1 complex was originally identified over fifteen years ago in budding yeast through
its physical association with RNA polymerase II. The Paf1 complex is now known to be …

The highly conserved Paf1 complex (PAF1C) plays critical roles in RNA polymerase II
transcription elongation and in the regulation of histone modifications. It has also been …

Numerous transcription accessory proteins cause alterations in chromatin structure that
promote the progression of RNA polymerase II (Pol II) along open reading frames (ORFs) …

Elongation factor Paf1C regulates several stages of the RNA polymerase II (Pol II)
transcription cycle, although it is unclear how it modulates Pol II distribution and progression …

Genetic and cell-based studies have implicated the PAF1 complex (PAF1C) in transcription-
associated events, but there has been no evidence showing a direct role in facilitating …

The conserved polymerase-associated factor 1 complex (Paf1C) plays multiple roles in
chromatin transcription and genomic regulation. Paf1C comprises the five subunits Paf1 …