The human reference genome is an essential tool for studying human genomes. The
standard reference genome is constructed from genomes of a few donors. The 1000 …

Summary form only given. The sequencing of the human genome would not have been
possible without software-and, because of the specific nature of this effort, very little of it was …

Inference of ancestral or extinct genomes is important in evolutionary biology, cancer
research and many other research areas. Whole-genome data has become readily …

Next generation sequencing (NGS) technologies have been applied extensively in many
areas of genetics and genomics research. A fundamental problem when comes to analyzing …

Human genomes are routinely compared against a universal reference. However, this
strategy could miss population-specific and personal genomic variations, which may be …

As the last decade of human genomics research begins to bear the fruit of advancements in
precision medicine, it is important to ensure that genomics' improvements in human health …

Background The non-reference sequences (NRS) represent structure variations in human
genome with potential functional significance. However, besides the known insertions, it is …

Notice of Violation of IEEE Publication Principles" Estimating neutral divergence amongst
Mammals for Comparative Genomics with Mammalian Scope" by Anup Bhatkar and JL …

The use of the human reference genome has shaped methods and data across modern
genomics. This has offered many benefits while creating a few constraints. In the following …

The current human reference genome is predominantly derived from a single individual and
it does not adequately reflect human genetic diversity. Here, we analyze 338 high-quality …