Sex-specific features of the correlation between GWAS-noticeable polymorphisms and hypertension in Europeans of Russia

T Ivanova, M Churnosova, M Abramova… - International Journal of …, 2023 - mdpi.com
The aim of the study was directed at studying the sex-specific features of the correlation
between genome-wide association studies (GWAS)-noticeable polymorphisms and …

Risk Effects of rs1799945 Polymorphism of the HFE Gene and Intergenic Interactions of GWAS-Significant Loci for Arterial Hypertension in the Caucasian Population …

T Ivanova, M Churnosova, M Abramova… - International Journal of …, 2023 - mdpi.com
The aim of this case-control replicative study was to investigate the link between GWAS-
impact for arterial hypertension (AH) and/or blood pressure (BP) gene polymorphisms and …

Replication of an African-American GWAS on blood pressure and hypertension in the Korean population

HS Jin, KW Hong, JE Lim, B Oh - Genes & Genomics, 2011 - Springer
Hypertension is a complex disease that is caused by the interaction of multiple genetic and
environmental risk factors, affecting 30% adult in industrialized countries. The identification …

The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population

B Soltész, P Pikó, J Sándor, Z Kósa, R Ádány, S Fiatal - PLoS One, 2020 - journals.plos.org
Estimating the prevalence of cardiovascular diseases (CVDs) and risk factors among the
Roma population, the largest minority in Europe, and investigating the role of genetic or …

A comprehensive study revealed SNP–SNP interactions and a sex-dependent relationship between polymorphisms of the CYP2J2 gene and hypertension risk

AV Polonikov, IV Ponomarenko, MA Bykanova… - Hypertension …, 2019 - nature.com
This study investigated whether common polymorphisms of cytochrome P450 2J2 (CYP2J2),
a major enzyme that controls the biosynthesis of vasoactive epoxyeicosatrienoic acids, are …

The combined impact of 12 common variants on hypertension in Japanese men, considering GWAS results

K Miyaki, NC Htun, Y Song, S Ikeda… - Journal of human …, 2012 - nature.com
Genome-wide association studies have identified several polymorphisms that appear to be
on hypertension-susceptible regions. We performed the current replication study in order to …

[HTML][HTML] A protective effect of GLY272SER polymorphism of GNB3 gene in development of essential hypertension and its relations with environmental hypertension …

AV Polonikov, MA Solodilova, VP Ivanov… - Terapevticheskii …, 2011 - edgccjournal.org
Aim. To study associations of C825T (rs5443) and G272S (rs16932941) polymorphisms of
GNB3 gene in Russian population of the Central Chernozem region with essential …

Haplotype association analysis of AGT variants with hypertension-related traits: the HyperGEN study

CC Gu, YPC Chang, SC Hunt, K Schwander, D Arnett… - Human …, 2006 - karger.com
Objective: Function of the renin-angiotensin system is important to human hypertension, but
its genetic etiology remains elusive. We set out to examine a hypothesis that multiple genetic …

Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: the millennium genome project for hypertension

K Kohara, Y Tabara, J Nakura, Y Imai, T Ohkubo… - Hypertension …, 2008 - nature.com
A multiple candidate-gene approach was used to investigate not only candidate genes, but
also candidate pathways involved in the regulation of blood pressure. We evaluated 307 …

A genome-wide association study of hypertension-related phenotypes in a Japanese population

Y Hiura, Y Tabara, Y Kokubo, T Okamura, T Miki… - Circulation …, 2010 - jstage.jst.go.jp
Background: Large-scale genome-wide association studies (GWAS) have been successful
in identifying genes that contribute to common diseases and phenotypes. A GWAS of …