Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer in adults.
When ccRCC is localized to the kidney, surgical resection or ablation of the tumor is often …

Clear cell renal cell carcinoma (ccRCC) frequently features a high level of tumor
heterogeneity. Elucidating the chromatin landscape of ccRCC at the single-cell level could …

The clear cell renal cell carcinoma (ccRCC) microenvironment consists of many different cell
types and structural components that play critical roles in cancer progression and drug …

Metastasis remains the main reason for renal cell carcinoma (RCC)–associated mortality.
Tyrosine kinase inhibitors (TKI) impart clinical benefit for most patients with RCC, but the …

Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and
metabolic heterogeneity. Here we perform genomic, transcriptomic, proteomic, metabolomic …

Diverse subtypes of renal cell carcinomas (RCCs) display a wide spectrum of
histomorphologies, proteogenomic alterations, immune cell infiltration patterns, and clinical …

To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma
(ccRCC), we performed comprehensive genomic, epigenomic, transcriptomic, proteomic …

Clear cell renal cell carcinoma (ccRCC) is one of the most immunologically distinct tumor
types due to high response rate to immunotherapies, despite low tumor mutational burden …

Background Clear cell renal cell carcinoma (ccRCC) is a particularly challenging tumor type
because of its extensive phenotypic variability as well as intra-tumoral heterogeneity (ITH) …

Simple Summary In recent years, several therapeutic advances have been made in clear
cell renal cell carcinoma (ccRCC) resulting in novel treatment regimens of increased …