Low level postnatal methylmercury exposure in vivo alters developmental forms of short-term synaptic plasticity in the visual cortex of rat

S Dasari, Y Yuan - Toxicology and applied pharmacology, 2009 - Elsevier
Methylmercury (MeHg) has been previously shown to affect neurotransmitter release. Short-
term synaptic plasticity (STP) is primarily related to changes in the probability of …

In vivo methylmercury exposure induced long-lasting epileptiform activity in layer II/III neurons in cortical slices from the rat

S Dasari, Y Yuan - Toxicology letters, 2010 - Elsevier
Prenatal and postnatal methylmercury (MeHg) exposure has been shown to increase
neuronal excitability and seizure susceptibility. To determine if early postnatal MeHg …

Disruption by methylmercury of membrane excitability and synaptic transmission of CA1 neurons in hippocampal slices of the rat

YK Yuan, WD ATCHIsoN - Toxicology and applied pharmacology, 1993 - Elsevier
In order to examine the effects of methylmercury (MeHg) on central synaptic transmission,
field potentials were recorded in the CA1 neurons of hippocampal slices by using …

Neurobehavioural and molecular changes induced by methylmercury exposure during development

C Johansson, AF Castoldi, N Onishchenko… - Neurotoxicity …, 2007 - Springer
There is an increasing body of evidence on the possible environmental influence on
neurodevelopmental and neurodegenerative disorders. Both experimental and …

Methylmercury reduces synaptic transmission and neuronal excitability in rat hippocampal slices

J Gutiérrez, AM Baraibar, E Albiñana, P Velasco… - … -European Journal of …, 2018 - Springer
In a previous study, we pointed out that the neurotoxic action evoked by methylmercury
(MeHg), a potent environmental pollutant responsible for fatal food poisoning, is associated …

Perinatal exposure to low-dose methylmercury induces dysfunction of motor coordination with decreases in synaptophysin expression in the cerebellar granule cells …

M Fujimura, J Cheng, W Zhao - Brain research, 2012 - Elsevier
Methylmercury (MeHg) is an environmental pollutant that is toxic to the developing central
nervous system (CNS) in children, even at low exposure levels. Perinatal exposure to MeHg …

Effects of sequential exposure to multiple concentrations of methylmercury in the rat hippocampal slice

SB Fountain, JD Rowan - Ecotoxicology and environmental safety, 2000 - Elsevier
Two experiments explored the effects of sequential exposure to multiple concentrations of
methylmercury (MeHg) on rat hippocampal slice synaptic transmission and excitability in …

Methylmercury increases glutamate extracellular levels in frontal cortex of awake rats

BI Juarez, ML Martınez, M Montante, L Dufour… - Neurotoxicology and …, 2002 - Elsevier
A current hypothesis about methylmercury (MeHg) neurotoxicity proposes that neuronal
damage is due to excitotoxicity following glutamate uptake alterations in the astrocyte. By …

Dose-dependent effects of methylmercury administered during neonatal brain spurt in rats

M Sakamoto, A Kakita, RB de Oliveira, HS Pan… - Developmental brain …, 2004 - Elsevier
Rapid brain growth occurs primarily during the third trimester in humans, whereas in rats it
occurs after parturition. Therefore, we hypothesized that the effects of methylmercury (MeHg) …

Changes in axonally transported proteins in the mature and developing rat nervous system during early stages of methyl mercury exposure

M Aschner - Pharmacology & Toxicology, 1987 - Wiley Online Library
It was established by means of SDS polyacrylamide gel electrophoresis that direct injections
of methyl mercury (10 μgHg) into the mature rat vitreous body of the eye decrease protein …