[HTML][HTML] Putative Cooperative ATP–DnaA Binding to Double-Stranded DnaA Box and Single-Stranded DnaA-Trio Motif upon Helicobacter pylori Replication Initiation …

P Jaworski, D Zyla-Uklejewicz… - International journal of …, 2021 - mdpi.com
oriC is a region of the bacterial chromosome at which the initiator protein DnaA interacts with
specific sequences, leading to DNA unwinding and the initiation of chromosome replication …

Assembly of helicobacter pylori initiation complex is determined by sequence-specific and topology-sensitive DnaA–oriC interactions

R Donczew, T Mielke, P Jaworski… - Journal of Molecular …, 2014 - Elsevier
In bacteria, chromosome replication is initiated by binding of the DnaA initiator protein to
DnaA boxes located in the origin of chromosomal replication (oriC). This leads to DNA helix …

Helicobacter pylori oriC —the first bipartite origin of chromosome replication in Gram-negative bacteria

R Donczew, C Weigel, R Lurz… - Nucleic acids …, 2012 - academic.oup.com
Binding of the DnaA protein to oriC leads to DNA melting within the DNA unwinding element
(DUE) and initiates replication of the bacterial chromosome. Helicobacter pylori oriC was …

The role of Helicobacter pylori DnaA domain I in orisome assembly on a bipartite origin of chromosome replication

M Nowaczyk‐Cieszewska… - Molecular …, 2020 - Wiley Online Library
The main roles of the DnaA protein are to bind the origin of chromosome replication (oriC),
to unwind DNA and to provide a hub for the step‐wise assembly of a replisome. DnaA is …

[HTML][HTML] Unique and universal features of Epsilonproteobacterial origins of chromosome replication and DnaA-DnaA box interactions

P Jaworski, R Donczew, T Mielke, M Thiel… - Frontiers in …, 2016 - frontiersin.org
In bacteria, chromosome replication is initiated by the interaction of the initiator protein DnaA
with a defined region of a chromosome at which DNA replication starts (oriC). While DnaA …

Architecture of bacterial replication initiation complexes: orisomes from four unrelated bacteria

A Zawilak-Pawlik, A Kois, J Majka… - Biochemical …, 2005 - portlandpress.com
Bacterial chromosome replication is mediated by single initiator protein, DnaA, that interacts
specifically with multiple DnaA boxes located within the origin (oriC). We compared the …

DiaA/HobA and DnaA: a pair of proteins co-evolved to cooperate during bacterial orisome assembly

A Zawilak-Pawlik, R Donczew, S Szafrański… - Journal of molecular …, 2011 - Elsevier
Replication of the bacterial chromosome is initiated by binding the DnaA protein to oriC.
Various factors control the ability of DnaA to bind and unwind DNA. Among them …

Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli

Y Sakiyama, K Kasho, Y Noguchi… - Nucleic acids …, 2017 - academic.oup.com
In Escherichia coli, the level of the ATP–DnaA initiator is increased temporarily at the time of
replication initiation. The replication origin, oriC, contains a duplex-unwinding element …

Near-atomic structural model for bacterial DNA replication initiation complex and its functional insights

M Shimizu, Y Noguchi, Y Sakiyama… - Proceedings of the …, 2016 - National Acad Sciences
Upon DNA replication initiation in Escherichia coli, the initiator protein DnaA forms higher-
order complexes with the chromosomal origin oriC and a DNA-bending protein IHF …

The atypical response regulator HP1021 controls formation of the Helicobacter pylori replication initiation complex

R Donczew, Ł Makowski, P Jaworski… - Molecular …, 2015 - Wiley Online Library
The replication of a bacterial chromosome is initiated by the D na A protein, which binds to
the specific chromosomal region ori C and unwinds duplex DNA within the DNA‐unwinding …