Cancer stem cells-emanated therapy resistance: implications for liposomal drug delivery systems

H Dianat-Moghadam, M Heidarifard… - Journal of controlled …, 2018 - Elsevier
It is verified that failure in cancer therapy by conventional chemotherapeutic agents arise
from cancer heterogeneity. That, a small subpopulation of cancer cells known as “cancer …

Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation

M Hashemi, F Ghadyani, S Hasani, Y Olyaee… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …

Nanomedicines for overcoming cancer drug resistance

T Hu, H Gong, J Xu, Y Huang, F Wu, Z He - Pharmaceutics, 2022 - mdpi.com
Clinically, cancer drug resistance to chemotherapy, targeted therapy or immunotherapy
remains the main impediment towards curative cancer therapy, which leads directly to …

Rationally designed nanovehicles to overcome cancer chemoresistance

YD Livney, YG Assaraf - Advanced drug delivery reviews, 2013 - Elsevier
Drug resistance is a primary hindrance towards curative cancer chemotherapy.
Nanotechnology holds great promise in establishing efficacious and innovative strategies to …

Molecular targeting of liposomal nanoparticles to tumor microenvironment

G Zhao, BL Rodriguez - International journal of nanomedicine, 2012 - Taylor & Francis
Liposomes are biodegradable and can be used to deliver drugs at a much higher
concentration in tumor tissues than in normal tissues. Both passive and active drug delivery …

Nanodelivery strategies in cancer chemotherapy: biological rationale and pharmaceutical perspectives

G Mattheolabakis, B Rigas, PP Constantinides - Nanomedicine, 2012 - Taylor & Francis
Nanotechnology is revolutionizing our approach to drug delivery, a key determinant of drug
efficacy. Here, we present cancer drug delivery strategies that exploit nanotechnology …

Liposomal cancer therapy: exploiting tumor characteristics

T Kaasgaard, TL Andresen - Expert opinion on drug delivery, 2010 - Taylor & Francis
Importance of the field: More than 10 million people worldwide are diagnosed with cancer
each year, and the development of effective cancer treatments is consequently of great …

The reversal of chemotherapy-induced multidrug resistance by nanomedicine for cancer therapy

S Liu, AR Khan, X Yang, B Dong, J Ji, G Zhai - Journal of Controlled …, 2021 - Elsevier
Multidrug resistance (MDR) of cancer is a persistent problem in chemotherapy. Scientists
have considered the overexpressed efflux transporters responsible for MDR and …

Optimizing druggability through liposomal formulations: new approaches to an old concept

D Bitounis, R Fanciullino, A Iliadis… - International Scholarly …, 2012 - Wiley Online Library
Developing innovative delivery strategies remains an ongoing task to improve both efficacy
and safety of drug‐based therapy. Nanomedicine is now a promising field of investigation …

Updates on responsive drug delivery based on liposome vehicles for cancer treatment

MP Nikolova, EM Kumar, MS Chavali - Pharmaceutics, 2022 - mdpi.com
Liposomes are well-known nanoparticles with a non-toxic nature and the ability to
incorporate both hydrophilic and hydrophobic drugs simultaneously. As modern drug …