Selenium, the thyroid, and the endocrine system

J Kohrle, F Jakob, B Contempré… - Endocrine reviews, 2005 - academic.oup.com
Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …

Selenium, selenoproteins and the thyroid gland: interactions in health and disease

L Schomburg - Nature reviews endocrinology, 2012 - nature.com
The trace element selenium is an essential micronutrient that is required for the biosynthesis
of selenocysteine-containing selenoproteins. Most of the known selenoproteins are …

[HTML][HTML] Selenium and endocrine systems

GJ Beckett, JR Arthur - Journal of endocrinology, 2005 - joe.bioscientifica.com
The trace element selenium (Se) is capable of exerting multiple actions on endocrine
systems by modifying the expression of at least 30 selenoproteins, many of which have …

Selenocysteine-containing proteins in mammals

VN Gladyshev, DL Hatfield - Journal of biomedical science, 1999 - karger.com
Since the recent discovery of selenocysteine as the 21st amino acid in protein, the field of
selenium biology has rapidly expanded. Twelve mammalian selenoproteins have been …

[HTML][HTML] A new human selenium-containing protein: Purification, characterization, and cDNA sequence

VN Gladyshev, KT Jeang, JC Wootton… - Journal of Biological …, 1998 - ASBMB
Selenium which occurs in proteins as the amino acid, selenocysteine, is essential for
numerous biological processes and for human health. A prominent 75 Se-labeled protein …

Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic

L Schomburg, U Schweizer, J Köhrle - Cellular and Molecular Life …, 2004 - Springer
Selenium (Se), once known only for its potential toxicity, is now well established as an
essential trace element for mammals. Insufficient Se intake predisposes to and manifests in …

Selenium in biology: facts and medical perspectives

J Köhrle, R Brigelius-Flohé, A Böck, R Gärtner… - 2000 - degruyter.com
Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …

Regulation and function of selenoproteins in human disease

FP Bellinger, AV Raman, MA Reeves… - Biochemical …, 2009 - portlandpress.com
Selenoproteins are proteins containing selenium in the form of the 21st amino acid,
selenocysteine. Members of this protein family have many diverse functions, but their …

Selenium and the control of thyroid hormone metabolism

J Köhrle - Thyroid, 2005 - liebertpub.com
Thyroid hormone synthesis, metabolism and action require adequate availability of the
essential trace elements iodine and selenium, which affect homeostasis of thyroid hormone …

Eukaryotic selenoproteins and selenoproteomes

AV Lobanov, DL Hatfield, VN Gladyshev - Biochimica et Biophysica Acta …, 2009 - Elsevier
Selenium is an essential trace element for which both beneficial and toxic effects in human
health have been described. It is now clear that the importance of having adequate amounts …