Synthesis and antitumor activity of some new pyrazolo [1, 5-a] pyrimidines
Abstract New series of pyrazolo [1, 5-a] pyrimidine derivatives 7a–i, 11a–c and Schiff bases
13a–c were synthesized and screened for their in vitro antitumor activity against three …
13a–c were synthesized and screened for their in vitro antitumor activity against three …
Synthesis and Anti‐tumor Activities of Novel Pyrazolo[1,5‐a]pyrimidines
J Li, YF Zhao, XL Zhao, XY Yuan… - Archiv der Pharmazie …, 2006 - Wiley Online Library
A series of novel pyrazolo [1, 5‐a] pyrimidines were designed and synthesized in order to
find novel potent anti‐tumor compounds. The structures of all the compounds were …
find novel potent anti‐tumor compounds. The structures of all the compounds were …
Synthesis and in vitro cytotoxic activity of novel pyrazolo[1,5-]pyrimidines and related Schiff bases
AS Hassan, TS Hafez, SAM Osman… - Turkish Journal of …, 2015 - journals.tubitak.gov.tr
Abstract The reaction of 5-amino-3-(4-methoxyphenylamino)-$ N $-aryl-1$ H $-pyrazole-4-
carboxamides\textbf {1a}--\textbf {c} with ethyl acetoacetate\textbf {2} and 2-(4 …
carboxamides\textbf {1a}--\textbf {c} with ethyl acetoacetate\textbf {2} and 2-(4 …
Synthesis and antitumor activity of novel 6-aryl and 6-alkylpyrazolo [3, 4-d] pyrimidin-4-one derivatives
MM El-Enany, MM Kamel, OM Khalil… - European journal of …, 2010 - Elsevier
A series of new 6-arylpyrazolo [3, 4-d] pyrimidin-4-ones and 6-alkylpyrazolo [3, 4-d]
pyrimidin-4-ones were synthesized. Some of the newly synthesized compounds were tested …
pyrimidin-4-ones were synthesized. Some of the newly synthesized compounds were tested …
Design, synthesis and antitumor evaluation of novel pyrazolopyrimidines and pyrazoloquinazolines
A series of N-aryl-7-aryl-pyrazolo [1, 5-a] pyrimidines 18a–u and N-aryl-pyrazolo [1, 5-a]
quinazolines 25a–c were designed and synthesized via the reaction of 5-aminopyrazoles …
quinazolines 25a–c were designed and synthesized via the reaction of 5-aminopyrazoles …
Synthesis, In Vitro Antimicrobial and Cytotoxic Activities of Some New Pyrazolo[1,5-a]pyrimidine Derivatives
A new series of pyrazole 4–7 and pyrazolo [1, 5-a] pyrimidine 8–13 were synthesized by
using a simple, efficient procedure, and screened for their in-vitro antimicrobial and …
using a simple, efficient procedure, and screened for their in-vitro antimicrobial and …
Some Pyrazole and Pyrazolo[3,4‐d]pyrimidine Derivatives: Synthesis and Anticancer Evaluation
AH Shamroukh, AE Rashad… - Archiv der …, 2014 - Wiley Online Library
5‐Amino‐1‐p‐tolyl‐1H‐pyrazole‐4‐carbonitrile (1) was used for the preparation of some
novel pyrazoles and pyrazolo [3, 4‐d] pyrimidines 2–10. Moreover, the cytotoxicity and in …
novel pyrazoles and pyrazolo [3, 4‐d] pyrimidines 2–10. Moreover, the cytotoxicity and in …
Synthesis, structural elucidation, and in vitro antitumor activities of some pyrazolopyrimidines and Schiff bases derived from 5-amino-3-(arylamino)-1H-pyrazole-4 …
TS Hafez, SA Osman, HAA Yosef, ASA EL-ALL… - Scientia …, 2013 - mdpi.com
Abstract The reaction of 5-amino-3-(arylamino)-1 H-pyrazole-4-carboxamides 1a, b with
acetylacetone 2 and arylidenemalononitriles 5a–c yielded the pyrazolo [1, 5-a]-pyrimidine …
acetylacetone 2 and arylidenemalononitriles 5a–c yielded the pyrazolo [1, 5-a]-pyrimidine …
Synthesis and Anticancer Activity of Some New Pyrazolo[3,4-d]pyrimidin-4-one Derivatives
3, 6-Dimethyl-1-phenyl-1 H-pyrazolo [3, 4-d][1, 3] oxazin-4-one (3) was prepared by
hydrolysis of ethyl 5-amino-3-methyl-1-phenyl-1 H-pyrazole-4-carboxylate (1) to afford the …
hydrolysis of ethyl 5-amino-3-methyl-1-phenyl-1 H-pyrazole-4-carboxylate (1) to afford the …
Design, synthesis, and antitumor evaluation of novel pyrazolo [3, 4-d] pyrimidine derivatives
A new series of pyrazolo [3, 4-d] pyrimidines has been synthesized. The new compounds
were tested for their antitumor activity on 60 different cell lines, and some of the compounds …
were tested for their antitumor activity on 60 different cell lines, and some of the compounds …